Results 61 to 70 of about 147,345 (227)

Gut Microbiota‐Isoallolithocholic Acid Crosstalk Promotes Calcium Oxalate Kidney Stone Formation via PARP1‐Mediated Parthanatos

Advanced Science, EarlyView.
ABSTRACT Bile acids have been implicated in calcium oxalate (CaOx) nephrolithiasis. Here, we employ multi‐omics approaches to identify isoallolithocholic acid (isoalloLCA) as the key bile acid elevated in the feces, serum, kidney, and urine of CaOx rats, confirmed by spatial metabolomics.
Zijian Zhou, Ruixi Yu, Xuan Zhou, Feng Shi, Zeyu Lin, Peng Gao, Lujia Wang, Ninghan Feng, Zhong Wu, Dawei Wang   +9 more
wiley   +1 more source

Broad cross-T cell immunity between emerging SARS-CoV-2 serotypes waved by spike-signature mutations

Emerging Microbes and Infections
Since its emergence in late 2019, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has continuously threatened human health through constantly arising variants with iterative immune escape abilities.
Yuanyuan Guo, Jinmin Tian, Peipei Guo, Xin Wang, Bingli Shang, Junying She, Mengjie Yang, George F. Gao, Jun Liu   +8 more
doaj   +1 more source

The Widespread Multidrug-Resistant Serotype O12 Pseudomonas aeruginosa Clone Emerged through Concomitant Horizontal Transfer of Serotype Antigen and Antibiotic Resistance Gene Clusters

mBio, 2015
The O-specific antigen (OSA) in Pseudomonas aeruginosa lipopolysaccharide is highly varied by sugar identity, side chains, and bond between O-repeats. These differences classified P. aeruginosa into 20 distinct serotypes. In the past few decades, O12 has
Sandra Wingaard Thrane, Véronique L. Taylor, Luca Freschi, Irena Kukavica-Ibrulj, Brian Boyle, Jérôme Laroche, Jean-Paul Pirnay, Roger C. Lévesque, Joseph S. Lam, Lars Jelsbak   +9 more
doaj   +1 more source

Surveillance et lutte contre l'épizootie 2013 de fièvre catarrhale ovine de sérotype 1 en Corse [PDF]

, 2013
Le 2 septembre 2013, des signes cliniques évocateurs de fièvre catarrhale ovine (FCO) ont été observés dans deux élevages ovins en Corse. Les analyses du laboratoire national de référence en virologie pour la FCO ont confirmé la présence du sérotype 1 du
Perrin, Jean-Baptiste, Gallois, Mélanie, Breard, Emmanuel, Calavas, Didier, Guis, Hélène, Sailleau, Corinne, Dominguez, Morgane, Hendrikx, Pascal, Clément, Thomas, Viarouge, Cyril, Zientara, Stéphan   +10 more
core  

SerpinA3 is an Endogenous TGF‐β Receptor Antagonist that Attenuates Cardiac Fibroblast Activation and Fibrotic Remodeling

Advanced Science, EarlyView.
SerpinA3 acts as an endogenous TGF‐β receptor antagonist that binds to the extracellular domain of TGFR‐1, thereby preventing TGFR‐1–TGFR‐2 complex formation. This receptor‐level blockade suppresses TGF‐β/Smad2/3 signaling, attenuates cardiac fibroblast activation, and extracellular matrix deposition, and ultimately alleviates pressure overload–induced
Hui Wang, Jieyu Cui, Chunlu Huang, Wanyi Guo, Tong Liu, Yi Zhu, Shuai Shao, Kangyin Chen, Jinlong He, Qiankun Bao   +9 more
wiley   +1 more source

Premier bilan de l'épizootie 2007 de FCO à sérotype 8 en France

, 2008
En 2007, l'épizootie de Fièvre Catarrhale Ovine (FCO) liée à l'introduction dans le Nord de l'Europe du sérotype 8 n'a pas épargné la France où 15 662 foyers ont été déclarés en 2007.
Balenghien, Thomas, Bouillet, Cédric, Coroller, Fabienne, Zanella, Gina, Zientara, Stéphan, Durand, Benoit   +5 more
core   +3 more sources

Distinct pattern of biofilm formation, adhesion, and invasion of Staphylococcus aureus to cardiac endothelial cells revealed its serotype-specific pathogenicity

Journal of Advanced Biotechnology and Experimental Therapeutics
Staphylococcus aureus is one of the major bacterial pathogens responsible for approximately one-third of infective endocarditis globally. For successful infection, S.
Mohammed Mohasin, Abdullah Al Saba, K. M. Kaderi Kibria, Rahena Yasmin, Muslim Idan Mohsin, Tania Rahman   +5 more
doaj   +1 more source

Contribution à l'étude immunologique de Pasteurella multocida : existence et importance d'un nouveau type, agent de la septicémie hémorragique des bovidés africains

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1961
cf. fichier PDF de l'article.
Pierre Perreau
doaj   +1 more source

Virulence and draft genome sequence overview of multiple strains of the swine pathogen Haemophilus parasuis. [PDF]

PLoS ONE, 2014
Haemophilus parasuis is the cause of Glässer's disease in swine, which is characterized by systemic infection resulting in polyserositis, meningitis, and arthritis.
Susan L Brockmeier, Karen B Register, Joanna S Kuehn, Tracy L Nicholson, Crystal L Loving, Darrell O Bayles, Sarah M Shore, Gregory J Phillips   +7 more
doaj   +1 more source

An RNA‐Binding Protein RBMS1 Promotes Endothelial Cell Autophagy to Maintain Vascular Homeostasis and Suppress Deep Vein Thrombosis

Advanced Science, EarlyView.
RBMS1, an RNA‐binding protein, restores vascular endothelial homeostasis by enhancing ATG3‐mediated autophagy, thereby attenuating thrombus formation and suggesting a potential avenue for further therapeutic exploration in DVT. ABSTRACT Deep vein thrombosis (DVT) is a prevalent vascular disorder characterized by aberrant coagulation within the deep ...
Chu Chu, Xinkui Liu, Nannan Fan, Xiaoyan Yu, Qiaoqiao Han, Yunhong Zhang, Wei Li, Yongqing Cai, Miaomiao Zhou, Fang Li, Feifei Shi, Zhen Zhang, Bin Wang, Xia Li   +13 more
wiley   +1 more source