Results 21 to 30 of about 100 (97)

Effect of Gabapentin Administered With Prednisolone, Ciclosporin or a Placebo on Clinical Outcomes and Motor Activity in Cats With Atopic Skin Syndrome: A Prospective, Blinded, Placebo‐Controlled Study

open access: yesVeterinary Dermatology, Volume 36, Issue 6, Page 814-824, December 2025.
Background: Gabapentin reportedly decreases central sensitisation, a disorder associated with chronic pruritus in humans, although this is not well documented in cats. Its combined use with the standard antipruritic therapy for feline atopic skin syndrome (FASS) is not yet described.
Jeanne Morency   +10 more
wiley   +1 more source

Generational effects in Down syndrome: Enriched environment enhances functionality without reducing Alzheimer's disease risk

open access: yesAlzheimer's &Dementia, Volume 21, Issue 10, October 2025.
Abstract INTRODUCTION Down syndrome (DS) is the leading cause of intellectual disability (ID) and a genetic form of Alzheimer's disease (AD). We wanted to assess whether generational changes have induced (1) milder ID with greater independence and (2) delayed AD diagnosis.
Lídia Vaqué‐Alcázar   +17 more
wiley   +1 more source

Body mass index and blood volume influence plasma biomarkers and positron emission tomography classification in preclinical Alzheimer's disease

open access: yesAlzheimer's &Dementia, Volume 21, Issue 10, October 2025.
Abstract INTRODUCTION Blood‐based biomarkers (BBMs) are promising tools for Alzheimer's disease (AD) diagnosis, but their accuracy may be affected by body mass index (BMI) and blood volume (BV) through dilution. We investigated how BMI and BV influence BBM concentrations and PET prediction.
Tovia Jacobs   +18 more
wiley   +1 more source

Different Contribution of Missense and Loss‐of‐Function Variants to the Genetic Structure of Familial and Sporadic Meniere Disease

open access: yesMedComm, Volume 6, Issue 10, October 2025.
This study examines the genetic basis of sporadic (SMD) and familial Meniere disease (FMD) by comparing rare protein‐coding variants using exome sequencing and gene burden analysis. FMD patients had a higher accumulation of missense and LoF variants, especially in genes linked to auditory and vestibular function.
Alberto M. Parra‐Perez   +5 more
wiley   +1 more source

Study of brain perfusion in adults with Down syndrome along the Alzheimer's disease continuum

open access: yesAlzheimer's &Dementia, Volume 21, Issue 9, September 2025.
Abstract INTRODUCTION We assessed pseudo‐continuous arterial spin labeling (pCASL) sensitivity to detect changes in cerebral blood flow (CBF) in adults with Down syndrome (DS) along the Alzheimer's disease (AD) continuum and explored the similarity with sporadic AD (sAD) hypoperfusion profile.
Maria Franquesa‐Mullerat   +21 more
wiley   +1 more source

Benefits and complications of fetal and postnatal surgery for open spina bifida: systematic review and proportional meta‐analysis

open access: yesUltrasound in Obstetrics &Gynecology, Volume 66, Issue 2, Page 135-146, August 2025.
ABSTRACT Objective To derive pooled estimates of maternal, fetal and pediatric outcomes up to the age of 30 months in patients undergoing pre‐ or postnatal surgery for open spina bifida (OSB). Methods A systematic search was conducted in MEDLINE, PubMed (non‐MEDLINE records), Embase, Web of Science, ClinicalTrials.gov, Cochrane Central Register of ...
Y. Kunpalin   +10 more
wiley   +1 more source

Costello Syndrome and Ophthalmologic Issues: Unveiling the Unseen

open access: yesAmerican Journal of Medical Genetics Part A, Volume 197, Issue 7, July 2025.
ABSTRACT Costello syndrome (CS) is an ultra‐rare condition belonging to the RASopathies, a group of disorders characterized by aberrant RAS/MAPK pathway signaling, which is involved in ocular development and in some eye pathologies. However, only a few studies assessing the ophthalmic features of individuals with CS are available.
Sofia Peschiaroli   +13 more
wiley   +1 more source

Clinical practice guideline of the Interamerican Society of Cardiology on primary prevention of cardiovascular disease in women. [PDF]

open access: yesArch Cardiol Mex, 2022
Del-Sueldo MA   +76 more
europepmc   +1 more source

Irritable Bowel Syndrome: News from an Old Disorder. [PDF]

open access: yesGE Port J Gastroenterol, 2020
Ferreira AI, Garrido M, Castro-Poças F.
europepmc   +1 more source

UEG Week 2025 Poster Presentations

open access: yes
United European Gastroenterology Journal, Volume 13, Issue S8, Page S803-S1476, October 2025.
wiley   +1 more source

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