Results 11 to 20 of about 84 (83)
Developmental Medicine &Child Neurology, EarlyView.Resumen Objetivo Describir la experiencia de progenitores de niños y adolescentes con síndrome de Dravet en relación con el impacto de las olas de calor o las altas temperaturas ambientales en las crisis epilépticas de sus hijos, así como las estrategias de afrontamiento empleadas.
Angel Aledo‐Serrano +8 more
wiley +1 more source
Descrição atualizada da paralisia cerebral
Developmental Medicine &Child Neurology, EarlyView.Resumo A paralisia cerebral (PC) é um termo descritivo amplamente utilizado para um espectro de deficiências motoras causadas por lesão ou malformação cerebral não progressiva ocorrida durante as fases iniciais do desenvolvimento. Avanços recentes nas áreas da genética, de pesquisa em inflamação e em neurofisiologia têm refinado a compreensão ...
Bernard Dan +5 more
wiley +1 more source
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, Volume 201, Issue 6, Page 406-419, September 2026.ABSTRACT Women with the FMR1 premutation (PM) are at increased risk for fragile X‐associated conditions (FXPAC), including cognitive and psychiatric features collectively termed fragile X‐associated neuropsychiatric disorders (FXAND). This study is the first to systematically investigate cognitive and psychiatric features in Italian female premutation ...
Federica Alice Maria Montanaro +5 more
wiley +1 more source
Alzheimer's &Dementia, Volume 22, Issue 8, August 2026.Abstract INTRODUCTION An extra copy of the amyloid precursor protein (APP) gene causes autosomal dominant Alzheimer's disease (AD) and AD in Down syndrome (DS), but the factors underlying variability in age at onset (AAO) remain unclear. We investigated whether sporadic AD risk variants modify AAO. METHODS We analyzed clinical and genetic data from 100
Joan Groeneveld +39 more
wiley +1 more source
Alzheimer's &Dementia, Volume 22, Issue 5, May 2026.Abstract INTRODUCTION Sleep and circadian rest–activity rhythm (RAR) disruption may bidirectionally relate to Alzheimer's disease (AD). Down syndrome (DS), the most common genetic cause of AD, presents sleep disorders, yet RAR patterns across the DS‐associated AD continuum remain uncharacterized. METHODS We analyzed 7‐day wrist actigraphy in 140 adults
Sandra Giménez +26 more
wiley +1 more source
Alzheimer's &Dementia, Volume 22, Issue 5, May 2026.Abstract INTRODUCTION This study investigates the evolution with disease progression and pathological correlates of peak width of skeletonized mean diffusivity (PSMD), a sensitive diffusion magnetic resonance imaging (MRI) marker of microvascular white matter (WM) injury, in sporadic Alzheimer's disease (sAD) and Down syndrome (DS)–associated AD (DSAD).
Alejandra O. Morcillo‐Nieto +27 more
wiley +1 more source
Joint Bayesian Nowcasting of Severe Acute Respiratory Illness and COVID‐19 Positives in Brazil
Statistics in Medicine, Volume 45, Issue 8-9, April 2026.ABSTRACT Surveillance of severe acute respiratory illness (SARI) in Brazil provides an early warning system for respiratory outbreaks, including COVID‐19, and statistical nowcasting methods are vital for correcting long and variable reporting delays that would otherwise hinder timely decision‐making. Coherent joint prediction of SARI and COVID‐positive
Alba Halliday +3 more
wiley +1 more source
Factors impacting survival in individuals with Down syndrome‐associated Alzheimer's disease
Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.Abstract INTRODUCTION Adults with Down syndrome (DS) are at high risk for Alzheimer's disease (AD), the leading cause of death in this population. Survival in DS after AD diagnosis appears shorter than in sporadic AD; however, the factors influencing survival remain poorly understood.
Bessy Benejam +24 more
wiley +1 more source
Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.Abstract INTRODUCTION White matter hyperintensities (WMH) are common in Down syndrome (DS), yet their longitudinal evolution and associations with Alzheimer's disease (AD) remain unclear. METHODS Longitudinal MRI study, including 80 DS adults and 53 euploid controls. WMH were segmented on serial FLAIR using a longitudinal pipeline.
Alejandra O. Morcillo‐Nieto +24 more
wiley +1 more source
Classification of Obesity Based on Weight History: Perceptions of People With Obesity
Clinical Obesity, Volume 16, Issue 1, February 2026.ABSTRACT Two Brazilian medical societies have proposed a new classification of obesity based on the maximum weight attained in an individual's lifetime, to be used in the clinical evaluation of individuals undergoing obesity treatment. This classification, which applies to adults aged 18 to 65 years, categorises people with obesity (PwO) who lose a ...
Bruno Halpern +9 more
wiley +1 more source