Results 161 to 170 of about 15,844,621 (256)

Betaine Promotes Milk Protein Synthesis via Alleviating Oxidative Stress Caused by NEFA in Mammary Epithelial Cells of Dairy Cows

Veterinary Medicine and Science, Volume 12, Issue 4, July 2026.
Betaine alleviated NEFA‐induced oxidative stress, which served as a central mechanistic link between fatty liver and mammary dysfunction, and concurrently improved milk protein synthesis via regulation of the Nrf2‐JAK2/STAT5/mTOR axis. ABSTRACT Background Fatty liver is highly prevalent in dairy cows and poses a significant challenge to the dairy ...
Wenyan Yan, Xinyuan Sun, Huanjie Shi, Zhenwang Li, Wenhui Li, Xiaoxiao Gao, Jihong Dong   +6 more
wiley   +1 more source

The Key Intermediate in Radical S‑Adenosyl-methionine Catalysis: Caught in the Act

ACS Central Science, 2019
Jonathan Rittle
doaj   +1 more source

S-Adenosylmethionine [PDF]

, 2020
openaire   +1 more source

Proteostasis Rebalancing by LET‐607 Deficiency Promotes Longevity

Aging Cell, Volume 25, Issue 7, July 2026.
LET‐607 enforces a trade‐off between UPRER and UPRcyto in C. elegans, maintaining a proteostatic balance optimized for development but suboptimal for longevity. LET‐607 deficiency suppresses UPRER but activates UPRcyto via attenuation of one‐carbon metabolism and H3K9 methylation, thereby enhancing cytosolic proteostasis and extending lifespan ...
Haixiang Tong, Wei Li, Pangui Yuan, Feng Li, Qin Liu, Shanshan Pang, Haiqing Tang   +6 more
wiley   +1 more source

An Integrative Methylation‐Metabolism Gene Signature Defines Prognosis and Immunosuppressive Microenvironment in Prostate Cancer

Chemical Biology &Drug Design, Volume 108, Issue 1, July 2026.
This study developed a 6‐gene prognostic model integrating methylation and amino acid metabolism to predict PCa outcomes and reveal immunosuppressive TME. ABSTRACT The synergistic crosstalk between epigenetic dysregulation and metabolic reprogramming underlies to prostate cancer (PCa) development and treatment resistance, yet an integrated prognostic ...
Chao Zhang, Likun Liu, Kai Wu
wiley   +1 more source

Maternal Obesity and MicroRNAs in Breast Milk: Implications for Infant Developmental Programming

Obesity Reviews, Volume 27, Issue 7, July 2026.
ABSTRACT This review explores the relationship between maternal obesity and alterations in the expression of microRNAs (miRNAs) in breast milk, highlighting how these changes may influence the developmental programming of the infant. Evidence suggests that maternal obesity can affect the bioactive composition of breast milk, including miRNA profiles ...
Gyslane M. Santos, Fabíola Isabel Suano de Souza, Luciana P. Pisani   +2 more
wiley   +1 more source

S-adenosylmethionine - a novel regulator of aspartate kinase [PDF]

, 1980
Peter J. Lea, Lea, P. J., Rognes, S. E., Miflin, B. J., Sven Erik Rognes, Benjamin J. Miflin   +5 more
core   +1 more source

THE FORMATION OF S-ADENOSYLMETHIONINE IN YEAST

Journal of Biological Chemistry, 1957
F, SCHLENK, R E, DEPALMA
openaire   +2 more sources

Structural Elucidation and Engineering of the (S)‐scoulerine 2‐O‐Methyltransferase Enabling Regioselective Epiberberine Biosynthesis in Coptis chinensis

Plant Biotechnology Journal, Volume 24, Issue 7, Page 4528-4545, July 2026.
ABSTRACT Protoberberine alkaloids are a characteristic group of natural products in Coptis plants known for their notable pharmacological activities. However, the structural similarity and the substrate promiscuity of their biosynthetic enzymes have left the precise synthetic pathways remain unclarified, posing challenges to regulate product formation.
Jun Song, Di Liu, Shi Chen, Yufeng Tan, Siyu Wang, Shihan Li, Yutong Qin, Guofeng Li, Xufang Tian, Lan Yang, Chong Yuan, Junbo Gou, Wei Huang, Shilin Chen, Yifei Liu   +14 more
wiley   +1 more source

S-adenosylmethionine as an epigenetic treatment of depression in adults with childhood trauma. [PDF]

Epigenomics
Alkema A, Schalkwijk W, Bohte E, Draisma L, Hoppe A, Koch C, Refuge V, Romberg B, Luykx JJ, Jans JJM, Cahn W, Regeer E, Boks MPM.   +12 more
europepmc   +1 more source