Results 161 to 170 of about 43,956,264 (204)

Position Effect Variegation of Penicillium rubens Genome and Application in Heterologous Production of the Plant‐Derived Anthraquinone Physcion

open access: yesMicrobial Biotechnology, Volume 19, Issue 10, October 2026.
This study constructed a PiggyBac transposon mediated mutagenesis system which was used to investigate the genomic position effect on heterologous production of physcion in Penicillium ruben. This PB platform enables efficient genetic engineering for secondary metabolite production. ABSTRACT The filamentous fungus Penicillium rubens is well known as an
Meng Wu   +5 more
wiley   +1 more source

From Regenerative to Degenerative Niche: Multicellular Crosstalk and Population Dynamics in Skeletal Muscle Aging

open access: yesAging Cell, Volume 25, Issue 10, October 2026.
Aging transforms the skeletal muscle microenvironment from a balanced, regenerative niche into a maladaptive, degenerative state. This review highlights how disrupted multicellular crosstalk drives chronic inflammation, fibrosis, and neuromuscular dysfunction, ultimately compromising tissue repair and fueling sarcopenia.
Seongwan Kim   +2 more
wiley   +1 more source

Toward understanding the catalytic mechanism for two classes of bacterial phospholipid N‐methyltransferases

open access: yesThe FEBS Journal, Volume 293, Issue 20, Page 6253-6271, October 2026.
Phospholipid N‐methyltransferases (Pmts) synthesize phosphatidylcholine in many bacteria. In this study, we compared the catalytic mechanisms of two bacterial Pmt classes: the Rhodobacter (R‐) and the Sinorhizobium (S‐) type. Representative enzymes for each class were derived from Rubellimicrobium thermophilum and Agrobacterium tumefaciens ...
Irina Shevyreva   +5 more
wiley   +1 more source

Dryland Soil Rewetting Induces Strong Volatile Organic Compound Emissions With Potential to Form Ozone and Aerosols

open access: yesGlobal Change Biology, Volume 32, Issue 10, October 2026.
Rainfall after drought triggers strong petrichor VOC emissions from dryland soils. These emissions are chemically diverse, shaped by aridity and soil microbial community, and can increase regional ozone and secondary organic aerosol formation potentials.
Andrea Ghirardo   +8 more
wiley   +1 more source

Extended Double Plasma Molecular Adsorption Sessions and Bilirubin Clearance: A Case Report

open access: yesHemodialysis International, Volume 30, Issue 4, Page 817-822, October 2026.
ABSTRACT Background The double plasma molecular adsorption system is an artificial‐liver treatment model combining the use of ion exchange resins and neutral microporous resins to remove toxins such as inflammatory cytokines without consuming large amounts of plasma and albumin. Given the relatively expensive consumables needed for Bilirubin adsorption,
Hui Ye   +7 more
wiley   +1 more source

Effects of n-benzothiazol-2-yl-benzensulfonamide and its derivatives on the synthesis of bacterial s-adenosylmethionine

open access: yes, 2015
The objective was to assess the impact of N-benzothiazol-2-ylbenzensulfonamide synthesis precursor signal molecules of quorum sensing in bacteria - S-adenosylmethionine (SAM)
Maliarchyk, I. O.
core  

Ya‐Jie‐Sha‐Ba Decoction Regulates Arachidonic Acid Metabolism to Treat Alcohol‐Associated Liver Disease by Activating PPARα–CYP4A14 Axis: Insights From Multi‐Omics Analysis and Experimental Validations

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 19, October 2026.
ABSTRACT Ya‐Jie‐Sha‐Ba decoction (YJSB), a traditional Dai medicinal formulation, has been widely used by the Dai ethnic group and has shown efficacy in alleviating alcohol‐associated liver disease (ALD). However, the molecular mechanism of YJSB in the management of ALD remains unclear.
Dehong Ma   +11 more
wiley   +1 more source

Huangqi Guizhi Wuwu Decoction Ameliorates Cachexia in Lung Cancer Mice Through Regulating Amino Acid Metabolism: Insights From Transcriptomics, Metabolomics and Experimental Validation

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 19, October 2026.
ABSTRACTThe effects and mechanisms of Huangqi Guizhi Wuwu Decoction (HGWD) in cancer cachexia remain unclear. We generated an in vivo cachexia model by implanting Lewis lung carcinoma cells into mice and treated animals with HGWD. We evaluated muscle function using grip strength and wire‐grip tests.
Yingjia Zhou   +9 more
wiley   +1 more source

PmWRKY‐10 Enhances Pine Wilt Disease Resistance by Promoting Pinosylvin Monomethyl Ether Biosynthesis Through Transcriptional Activation of PmPMT2‐1

open access: yesMolecular Plant Pathology, Volume 27, Issue 10, October 2026.
We identified a PmWRKY‐10→PmPMT2‐1→PME defence pathway in Pinus massoniana against pine wilt disease. PmWRKY‐10 activates PmPMT2‐1 to promote the accumulation of the nematicidal metabolite PME. This discovery reveals the mechanism of stilbene‐mediated resistance and provides key genetic targets for forest management.
Ziyan Nie   +6 more
wiley   +1 more source

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