Results 151 to 160 of about 15,844,621 (256)

METABOLISM OF S-ADENOSYLMETHIONINE IN SACCHAROMYCES CEREVISIAE DURING ASCOSPORE GERMINATION AND OUTGROWTH. [PDF]

, 1976
METABOLISM OF S-ADENOSYLMETHIONINE IN SACCHAROMYCES CEREVISIAE DURING ASCOSPORE GERMINATION AND ...
SUN-JIN. CHOIH (7980731)
core  

Adjunctive S-adenosylmethionine (SAMe) in treating non-remittent major depressive disorder: An 8-week double-blind, randomized, controlled trial [PDF]

, 2018
Adjunctive S-adenosylmethionine (SAMe) in treating non-remittent major depressive disorder: An 8-week double-blind, randomized, controlled ...
S Nazareth (13526923), S Chamoli (13367193), K Savage (11760017), J Sarris (9773810), P MacDonald (13358301), R Menon (10747290), Michael Berk (13060851), L Adams (13299669), C Ng (9850451), G Oliver (9334937), L Cribb (13366488), C Stough (13417722), C Bousman (13330056), D Mischoulon (13366509), J Murphy (3426530), GJ Byrne (9879248)   +15 more
core  

Exercise, Demethylase FTO, Neurological Disorders, and Neuropathic Pain: Potential Molecular Mechanisms

CNS Neuroscience &Therapeutics, Volume 32, Issue 7, July 2026.
This review summarizes the role of FTO‐regulated m6A modification in Alzheimer's disease, Parkinson's disease, depression, and neuropathic pain. Exercise may ameliorate neural plasticity and neuronal excitability by downregulating FTO and enhancing m6A modification. We propose that FTO could serve as a potential epigenetic target through which exercise
Yanan Zheng, Yili Zheng, Peijie Chen, Xueqiang Wang   +3 more
wiley   +1 more source

Expression of rat liver S-adenosylmethionine synthetase in Escherichia coli results in two active oligomeric forms [PDF]

, 1994
5 pages, 3 figures.A cDNA containing the complete coding sequence for rat liver S-adenosylmethionine synthetase was cloned into the prokaryotic expression vector pT7-7 and expressed in Escherichia coli BL21(DE3).
Pajares, María Ángeles, Mato, José M., Álvarez, Luis, Mingorance, Jesús   +3 more
core  

Strain‐Specific Biotransformation of Grape Marc by Lactic Acid Bacteria: Genomic Validation and Gut Microbiota Modulation

Food Frontiers, Volume 7, Issue 4, July 2026.
ABSTRACT Grape marc (GM) is a polyphenol‐rich winery byproduct that remains underutilized due to its complex fiber matrix, which limits the bioaccessibility of bound phenolics. While lactic acid fermentation (LAF) can enhance the release of these compounds, the strain‐specific metabolic fate of GM phenolics during digestion and colonic fermentation ...
Ziyao Liu, Hanjing Wu, Brendan Holland, Colin J. Barrow, Hafiz A. R. Suleria   +4 more
wiley   +1 more source

First Revision of the Guidelines for the Diagnosis and Management of Remethylation Disorders

Journal of Inherited Metabolic Disease, Volume 49, Issue 4, July 2026.
ABSTRACT This guideline summarizes diagnostic and therapeutic approaches based on a systematic literature review and evidence evaluation using the GRADE methodology. Given the limited high‐quality data, expert consensus was additionally obtained through a modified Delphi process.
Giorgia Olivieri, Andrea Bordugo, Birute Burnyte, Alessandro Costetti, Maria‐Luz Couce, Luisa Diogo, Francois Feillet, D. Sean Froese, Benedetta Greco, Jean‐Louis Gueant, Luciana Hannibal, Friederike Hörster, Viktor Kožich, Giancarlo La Marca, Irini Manoli, Fanny Mochel, Lorenzo Orazi, Belén Pérez, Manuel Schiff, Bernd C. Schwahn, Ida Schwartz, Karolina M. Stepien, Jolanta Sykut‐Cegielska, Trine Tangeraas, Rolf H. Zetterström, Carlo Dionisi‐Vici, Martina Huemer   +26 more
wiley   +1 more source

Vitamin‐Responsive Disorders: From Molecular Basis to Clinical Presentation and Therapy

Journal of Inherited Metabolic Disease, Volume 49, Issue 4, July 2026.
ABSTRACT Vitamin‐dependent cofactors are essential for numerous metabolic reactions, and defects affecting their uptake, conversion, utilisation, or regeneration constitute a heterogeneous group of inherited metabolic disorders (IMDs). Although dietary vitamin intake is sufficient to sustain coenzyme synthesis in healthy individuals, it is insufficient
Cécile Acquaviva, Yann Nadjar, Manuel Schiff, Christine Vianey‐Saban, Alain Fouilhoux, Jean‐François Benoist   +5 more
wiley   +1 more source

Cancer Heterogeneity and Cancer Cell Plasticity: Molecular Mechanisms and Precision Therapy

MedComm, Volume 7, Issue 7, July 2026.
Tumor progression is driven by heterogeneity occurring across multiple biological scales. At the molecular level, tumor cells exhibit alterations across distinct omics layers, including genomic mutations, epigenomic reprogramming, transcriptional changes, and proteomic remodeling, collectively shaping tumor cell phenotypes and functional states.
Hanwen Hu, Zhixing Hao, Lili Li, Huiying Liu, Chenghui Yang, Zhen Wang   +5 more
wiley   +1 more source

Inhibition of phosphatidylethanolamine biosynthesis by S‐adenosylmethionine [PDF]

FEBS Letters, 1976
Plantavid, M., Maget-Dana, R., Douste-Blazy, L.   +2 more
openaire   +2 more sources

Nicotinamide N‐Methyltransferase Epigenetically Activates Fibronectin 1 Through H3K9me3 Remodeling in Clear Cell Renal Cell Carcinoma

MedComm, Volume 7, Issue 7, July 2026.
Upregulation of NNMT in ccRCC is associated with tumor stage and poor prognosis. Mechanistically, NNMT reduces SAM levels, thereby decreasing H3K9me3 modification and promoting FN1 transcription. NNMT inhibitor effectively suppresses tumor progression, providing compelling evidence for its potential as a novel target for therapeutic intervention in ...
Lingling Wang, Yueyang Wang, Qizheng Han, Xiao Zhou, Chenxia Wu, Honghe Zhang, Zhiyong Liang, Maode Lai   +7 more
wiley   +1 more source