Results 131 to 140 of about 43,956,264 (204)
Dietary crude protein and methionine interact significantly in Japanese quail. Optimal methionine ranges from 0.50%–0.70% depending on protein level and phase. Best grower performance occurs at 25% CP with 1.30% Met, yielding 161.84 g male weight gain. Females show superior breast yield (30.90%).
Elyas Piroz‐Maleki +4 more
wiley +1 more source
ENDOR Spectroscopy Shows That Guanine N1 Binds to [4Fe−4S] Cluster II of the S-Adenosylmethionine-Dependent Enzyme MoaA: Mechanistic ...
Hermann Schindelin (440504) +6 more
core +1 more source
Targeted metabolomics of gill and mantle tissues from five marine bivalve species spanning lifespans from approximately 30 to over 500 years revealed longevity‐associated metabolic signatures. Longer‐lived species exhibited reduced free amino acid pools, lactate, pyruvate‐related ratios, fumarate and malate, alongside increased succinate‐to‐fumarate ...
Pauline Bertrand +4 more
wiley +1 more source
A sterospecific colorimetric assay for (s,s)-Adenosylmethionine quantification based on thiopurine methyltransferase-catalyzed thiol methylation [PDF]
S-Adenosyl-L-methionine (AdoMet or SAM) that is biologically synthesized by AdoMet synthetase bears an s-configuration at the sulfur atom. The chiral sulfonium spontaneously racemizes to form a mixture of s-and R-isomers of AdoMet under physiological ...
Wan, Wei +3 more
core
This review examines how histone modifications integrate aging, metabolic dysfunction and neuroinflammation to shape persistent, cell‐type‐specific chromatin states in Alzheimer's disease. By distinguishing causal regulation from association through perturbation, persistence and reversibility, it highlights metabolic–epigenetic feedback loops and ...
Junyi Liang +7 more
wiley +1 more source
Methionine Regulates Antitumour Function of CD8+ T Cells Through Polyamine Synthesis
Methionine restriction in vitro enhances CD8+ T cell effector function by suppressing polyamine synthesis and progressively induces the co‐expression of PD‐1 and TIM‐3. Consistently, sustained dietary methionine restriction diminishes the efficacy of adoptive T cell therapy (ACT) and promotes the expression of terminal exhaustion‐associated markers ...
Tian Zhao +16 more
wiley +1 more source
We extend a widely used C3‐photosynthesis model to account for various photorespiratory bypasses, thereby, providing a useful resource and framework that enforces future novel bypass work and scrutinize if the results go counter to theory. Our model analyses show that of the 17 published bypass pathways, full‐decarboxylating bypasses (that have been ...
Xinyou Yin +3 more
wiley +1 more source
The synthesis of the N-methyl analogue of S-adenosylmethionine; N.M.R. observation of diastereomers
The N-methyl analogue (1; X = N-Me) of S-adenosylmethionine has been synthesized; the intermediates and the end-product are racemic at the amino acid α-carbon, and show diastereomeric splitting in their 13C n.m.r. spectra.
NPB Dudman, M Davis, HF White
core +1 more source
Regulation of Sleep and Circadian Rhythms by S-Adenosylmethionine-Producing Probiotics
Current first-line medications for sleep disorders often overlap with antidepressants, yet their effectiveness remains suboptimal, highlighting the urgent need for novel therapeutic strategies based on new mechanisms.
Peijun Tian +7 more
doaj +1 more source
A maternal western diet (WD) and betaine supplementation during suckling influence metabolic programming. A maternal WD induced adverse metabolic effects in offspring, accompanied by altered FGF21‐related gene expression and decreased Akkermansia muciniphila abundance.
Rocío A. Martín‐Chamorro +4 more
wiley +1 more source

