Results 121 to 130 of about 43,956,264 (204)

Effect of methionine loading on 5-methyltetrahydrofolate, S-adenosylmethionine and S-adenosylhomocysteine in plasma of healthy humans.

, 1996
1. Elevated plasma homocysteine concentration, either in the fasting state or after methionine loading, is an independent risk factor for vascular disease in man.
Angst CP, Haefeli WE, Fowler B, Browne G, Loehrer FM, Frick G   +5 more
core   +1 more source

Effects of Rosmarinic Acid on L‐Methionine‐Induced Behavioral Impairments and Disruptions in Hippocampal Neurogenesis in the Adult Rat

Food Science &Nutrition, Volume 14, Issue 11, November 2026.
“Excessive L‐methionine (L‐met) intake impairs spatial (NOL) and recognition (NOR) memory, suppresses cell proliferation and vascular‐associated proliferating cells (Ki‐67 and Ki‐67/RECA‐1) and neuronal survival (BrdU/NeuN), and increases cell‐cycle arrest (p21) in the hippocampal dentate gyrus of adult rats.
Salinee Naewla, Jirawadee Chaithum, Tanaporn Anosri, Nataya Sritawan, Anusara Aranarochana, Jariya Umka Welbat, Peter Wigmore, Apiwat Sirichoat   +7 more
wiley   +1 more source

Density Functional Theory Investigation of As(III) S‑Adenosylmethionine Methyltransferase

ACS Omega, 2020
Seth A. Friesen, Jesse B. Elder, Eric A. C. Bushnell   +2 more
doaj   +1 more source

Betaine Attenuates Cuprizone‐Induced Cortical Demyelination: The Role of the WNT4/mTOR Signalling Pathway in Regulating Astrogliosis and Synaptic Integrity

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 11, November 2026.
Betaine helps to restore the dysfunctional communication between oxidative stress and inflammation, and it also improves demyelination in cuprizone‐induced demyelinating disease within the cerebral cortex. ABSTRACT Cortical grey matter pathology manifests early demyelinating diseases and is a primary driver of permanent neurological impairment.
Yara M. Said, Heba‐Tallah Abd Elrahim Abd Elkader, Gihad Jamal Bekheet, Sherine Abdel Salam, Amina E. Essawy   +4 more
wiley   +1 more source

Increased sensitivity to oxidative injury in chinese hamster ovary cells stably transfected with rat liver S-adenosylmethionine synthetase cDNA [PDF]

, 1996
7 pages, 6 figures, 4 tables.-- et al.Chinese hamster ovary cells were stably transfected with rat liver S-adenosylmethionine synthetase cDNA. As a result, S-adenosylmethionine synthetase activity increased 2.3-fold, an effect that was accompanied by ...
Pajares, María Ángeles, Mato, José M., Álvarez, Luis, García, Concepción, Sánchez-Góngora, Estrella   +4 more
core  

Vitamin B12 alleviates spliceosomopathy via phospholipid remodeling

Nature Communications
mRNA splicing represents a fundamental level of gene regulation that alters proteomic diversity and cellular state. Its dysfunction can profoundly rewire metabolism, yet underlying mechanisms remain elusive.
Jonathan Kölschbach, Hormos S. Dafsari, Emily Baum, Anna Löhrke, Chun Kew, Ivan Dikic, Wenming Huang, Adam Antebi   +7 more
doaj   +1 more source

Biological activities and bioactive constituents of Flammulina velutipes: An updated systematic review

Journal of the Science of Food and Agriculture, Volume 106, Issue 14, Page 8298-8314, November 2026.
Abstract Flammulina velutipes (enokitake) is an edible mushroom recognized for both its nutritional and medicinal properties. It exhibits a broad spectrum of biological activities, including antioxidant, anti‐inflammatory, antitumor, immunomodulatory, and gut microbiota‐regulating effects.
Rıdvan Özgen, Didem Şöhretoğlu, Ayşe Kuruüzüm‐Uz   +2 more
wiley   +1 more source

Effects of calcium, S-adenosylmethionine, S-(2-aminoethyl)-L-cysteine, methionine, valine and salt concentration on rice aspartate kinase isoenzymes

, 2015
The activities of two aspartate kinase (EC 2.7.2.4) isoenzymes that have been partially purified from developing rice seeds, were studied in the presence of calcium, calmodulin inhibitors, S-adenosylmethionine, S-(2-aminoetyl)-L-cysteine, methionine ...
Gaziola, SA, Lugli, J, Azevedo, RA
core   +1 more source

Substrate‐Dependent Crosslinking by the Cytochrome P450 From Aminopyruvatide Biosynthesis

Angewandte Chemie, Volume 138, Issue 44, 26 October 2026.
Substitutions in the aminopyruvatide precursor peptide altered the C─C linkage formed from a YLY motif by the P450 ApyO to a N─C linkage in a WLY motif. Moreover, constitutional isomers crosslinked by C─C and C─O linkages were formed from YYY or YWY motifs. ABSTRACT Cytochrome P450s catalyze an array of reactions including crosslinking of aromatic side
Chandrashekhar Padhi, Dinh T. Nguyen, Lingyang Zhu, Lide Cha, Jesse W. Wald, Douglas A. Mitchell, Wilfred A. van der Donk   +6 more
wiley   +2 more sources

The Role of Astrocytes in the Inflammatory Response in Neurodiseases

MedComm, Volume 7, Issue 11, November 2026.
Reactive astrocyte‐mediated pathogenic mechanisms in neurodegenerative diseases Schematic representation of key astrocytic pathways contributing to pathology in the pathogenesis of AD, PD, ALS, and HD. In AD, astrocytes exhibit Aβ plaque‐associated activation characterized by GFAP/S100β upregulation, accompanied by impaired EAAT2‐mediated glutamate ...
Shijun Peng, Lepeng Wang, Jia Ouyang, Ruen Liu   +3 more
wiley   +1 more source