Results 111 to 120 of about 60,211 (294)

Methionine Protects Mammary Cells against Oxidative Stress through Producing S‐Adenosylmethionine to Maintain mTORC1 Signaling Activity [PDF]

, 2021
Heju Zhong, Peiqiang Yuan, Yunxia Li, Dolores I. Batonon-Alavo, Caroline Deschamps, Bin Feng, Xiaoling Zhang, Lianqiang Che, Yan Lin, Shengyu Xu, Jian Li, Yong Zhuo, Gang Tian, Jiayong Tang, Xuemei Jiang, Lingjie Huang, Caimei Wu, De Wu, Zhengfeng Fang   +18 more
openalex   +1 more source

Polyamine, peroxidase activity and total protein content during storage of bird-of-paradise [PDF]

, 2015
The present study was aimed to the determination of the effect of storage on some biochemical characteristics (PAs content, POX activity and total protein content) of flower tissue of bird-of-paradise.
de Moura, Fabiana Bezerra, de Souza, Angela Vacaro, Lima, Giuseppina Pace Pereira, Sim\uf5es, Adriano do Nascimento, Vianello, Fabio, Vieira, Marcos Ribeiro da Silva   +5 more
core  

Cannabidiol and cannabigerol ameliorate steatotic liver disease via phosphocreatine buffering and lysosomal restoration

British Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) and cannabigerol (CBG) alleviate hepatic steatosis in obese mice by shifting energy buffering towards phosphocreatine and enhancing lysosomal lipid degradation and trafficking. These effects are associated with increased creatine kinase activity and lysobisphosphatidic acid (LBPA) levels, highlighting a previously unrecognised ...
Radka Kočvarová, Shahar Azar, Bella Agranovich, Ifat Abramovich, Saveliy Kirillov, Alina Nemirovski, Saja Baraghithy, Inbar Plaschkes, Emmanuelle Merquiol, Alexander Rouvinski, Galia Blum, Liad Hinden, Joseph Tam   +12 more
wiley   +1 more source

Algorithm of management of patient with alcohol-induced liver disease

Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2011
The aim of review. To present main pathogenic aspects of development of alcohol-induced liver disease (ALD), principles of diagnostics and treatment of this disease.Original positions.
M. V. Mayevskaya, M. A. Morozova
doaj  

Enzymatic synthesis of bioactive quinolones and (thio)coumarins by fungal type III polyketide synthases

The FEBS Journal, EarlyView.
Quinolones are valuable scaffolds for drug discovery but are rare in nature. Here, we show that two fungal enzymes, AthePKS and FerePKS, can generate 2‐quinolones and two additional heteroaromatic scaffolds. Using AthePKS, we designed an artificial enzymatic cascade towards an antimicrobial quinolone from a simple precursor and implemented it in E ...
Nika Sokolova, Angelina Osipyan, Lili Zhang, Matthew R. Groves, Sandy Schmidt, Kristina Haslinger   +5 more
wiley   +1 more source

The Bifunctional Active Site of S-Adenosylmethionine Synthetase [PDF]

, 1999
John Taylor, George D. Markham
openalex   +1 more source

S‐Adenosylmethionine (SAM) hydrolases counter increased SAM epimerisation in thermophilic archaea

The FEBS Journal, EarlyView.
S‐Adenosyl‐l‐methionine (SAM) is a vital enzyme cofactor. Epimerisation at the sulfonium centre of biologically active (SS,SCα)‐SAM is driven by heat, yielding biologically inactive (RS,SCα)‐SAM. Here, two novel archaeal SAM hydrolases from the thermophilic Sulfolobus acidocaldarius and the halophilic Haloferax volcanii are shown to cleave (RS,SCα)‐SAM.
Agnes Bartels, Michael K. F. Mohr, Phillip Nußbaum, Marie Joest, Bianca Wassmer, Laurent Rasquin, Sonja‐Verena Albers, Jennifer N. Andexer   +7 more
wiley   +1 more source

Changes in S-adenosylmethionine and GSH homeostasis during endotoxemia in mice [PDF]

, 2008
Kwangsuk Ko, Heping Yang, Mazen Noureddin, Ainhoa Iglesia-Ara, Meng Xia, Conrad Wagner, Zigmund Luka, José M. Mato, Shelly C. Lu   +8 more
openalex   +1 more source

Toward understanding the catalytic mechanism for two classes of bacterial phospholipid N‐methyltransferases

The FEBS Journal, EarlyView.
Phospholipid N‐methyltransferases (Pmts) synthesize phosphatidylcholine in many bacteria. In this study, we compared the catalytic mechanisms of two bacterial Pmt classes: the Rhodobacter (R‐) and the Sinorhizobium (S‐) type. Representative enzymes for each class were derived from Rubellimicrobium thermophilum and Agrobacterium tumefaciens ...
Irina Shevyreva, Lena Sophie Fritsch, Leander Mika Koch, Anton Effing, Meriyem Aktas, Franz Narberhaus   +5 more
wiley   +1 more source

Overexpression of S-adenosylmethionine decarboxylase (SAMDC) activates the maternal program of apoptosis shortly after MBT in Xenopus embryos [PDF]

, 2000
Masayuki Kai, Tomoya Higo, Jun’ichi Yokoska, Chikara Kaito, Eri Kajita, Hiroshi Fukamachi, Eiji Takayama, Kazuei Igarashi, K. Shiokawa   +8 more
openalex   +1 more source