Results 101 to 110 of about 1,465,890 (271)

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

Exercice de style [PDF]

, 2016
We present the construction and implementation of an 8-bit S-box with a differential and linear branch number of 3. We show an application by designing FLY, a simple block cipher based on bitsliced evaluations of the S-box and bit rotations that targets ...
Karpman, Pierre
core   +1 more source

Design and Research of S-Box Based on Dynamic Strategy

Dianxin kexue, 2015
Block cipher encryption is the mainstream method of information security application,and it has been widely used in wireless sensor networks.S-box which is one of the core modules of block cipher algorithm has a direct and significant impact on the ...
Zhouquan Du, Qijian Xu, Jie Zhang, Xudong Zhong, Zhulin An   +4 more
doaj   +2 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

IMPLEMENTASI KRIPTOGRAFI AES DAN OTP DALAM MEMBANGKITKAN KODE OTENTIKASI UNTUK AKTIVASI ONLINE MEMBER BARU YANG DIKIRIM MELALUI SMS [PDF]

, 2016
Pembuatan Akun palsu yang digunakan untuk perbuatan tidak baik sangat merugikan dan membuat buruk citra pemilik dan situs media sosial atau situs jual beli online miliknya, oleh karena itu diperlukan tindakan pencegahan agar pengguna tidak mendaftarkan ...
Ramadhan, Iman Muhamad
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Обчислювальні характеристики підстановочно-перестановочних мереж з s-боксами розміром 16х16 біт [PDF]

, 2011
В цій статті розглянута реалізація блочного шифру, який оснований на архітектурі гніздової постановочно-перестановочной сети (nested SPN), c блоками підстановки (S-боксами) розміром 16х16 біт в комп`ютерних системах.
Бевз, О. М.
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source