Results 51 to 60 of about 28,447,240 (259)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

De novo myasthenia gravis in a patient with malignant melanoma after concurrent SARS-CoV-2 vaccination and immune checkpoint inhibitor therapy: Case report and literature review

open access: yeseNeurologicalSci
In recent years, the advent and increasingly common use of immune checkpoint inhibitors (ICIs) in cancer treatment have been notable. While ICIs have shown relatively better toxicity profiles compared to traditional chemotherapy agents, they are linked ...
Mohadese Shahin   +4 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Using community development theory to improve student engagement in online discussion: a case study

open access: yesResearch in Learning Technology, 2009
Online discussion can be designed to develop the skills and confidence of students as well as providing an opportunity for constructing knowledge. If students decide not to participate or join too late, they put their own development and the quality of ...
Elisabeth Skinner
doaj   +1 more source

REVISITING KUBLER-ROSS’S FIVE STAGES OF GRIEF: SOME COMMENTS ON THE IPHONE 5

open access: yesJournal of Social Sciences, 2013
Following the recent launch of Apple’s fifth genera tion of the iPhone product line, this study specifi cally looks at the feedback from consumers who experience grief as a result of a let-down in anticipation. This st udy randomly extracts some useful consumer comments from online forums, reviews and Tumblr illustrations.
openaire   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

ROMANIA’S FIRST FIVE YEARS IN THE EUROPEAN UNION. A SHORT ASSESSMENT [PDF]

open access: yesAnnals of the University of Oradea: Economic Science, 2012
It’s been more than 5 years since our country has joined the European Union, on January the 1st 2007. It’s been a long road, as fulfilling the Copenhagen criteria had not been an easy task. But was it all worth it? Are we better off today, five years
VADASAN Ioana
doaj  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Strategic analysis of the construction industry in Spain

open access: yesManagement Letters/Cuadernos de Gestión, 2011
The construction sector has, in Spain, a remarkable importance, due to the contribution to GDP, around 10%, and employment (10%) and the wide business network it includes. The present economic situation and the residential market saturation have led to a
Rodrigo Martín García   +1 more
doaj  

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