Results 61 to 70 of about 28,447,240 (259)
Sequence characterization and evolutionary analysis of S-RNase gene among five genera Pomoideae [PDF]
Guoshu xuebao[Objective] In order to avoid self-pollination, self-incompatibility is a common phenomenon in 5 genera in Pyridae fruit trees during evolution. In order to understand the latest isolation and identification of S-RNase gene in pear incompatibility, we ...
LIANG Wenjie, XIE Zhiliang, Wuyun Tana
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
“Obesity–Years” Burden May Predict Reversibility in Heart Failure With Preserved Ejection Fraction
Frontiers in Cardiovascular Medicine, 2022 Anand Chockalingam, Anand Chockalingam
doaj +1 more source
Lived experiences of farmworkers from five U. S. states during the COVID-19 pandemic
Frontiers in Public HealthObjectiveThe nexus of farmworker and COVID-19 peer-reviewed research has yet to be advanced by qualitative analysis that: (1) focuses on multiple dimensions of farmworker’s daily life and (2) uses a geographically diverse sample.
Keren Herrán +4 more
doaj +1 more source
Precision testing method of five-axis NC machine tool based on ‘S’ specimen cutting
The Journal of Engineering, 2019 ‘S’ specimen through its unique profile features makes it possible to fully mobilise the five-axis linkage function in the five-axis finishing stage. The continuous rotation direction of the rotating axis not only reflects the static error of the machine
Mengying Xu, Hongjun Wang
doaj +1 more source
eIFL's five years of OA advocacy in South Africa
, 2009 Gaining the momentum: eIFL marks five year commitment to Open Access in South Africa, <em> eIFL.net </em> . May 2009.
openaire +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source