Results 81 to 90 of about 4,159,249 (256)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Minimizing the Risk of Wrong-site Dermatologic Surgery: The Five “I”s Process

Plastic and Reconstructive Surgery, Global Open, 2023
Elizabeth Rajiah, MRCS (Eng), Ana Borges, MRCS, Mahaba Hamad, MRCS, Trinettra Ruben, Ruben Y. Kannan, FRCS(Plast), PhD   +4 more
doaj   +1 more source

Catherine Emerson, Who Witnessed and Narrated the ‘Banquet of the Pheasant’ (1454)? A Codicological Examination of the Account ‘s Five Versions

Studi Francesi, 2004
C. E. analyse d’abord rapidement la tradition manuscrite du «Banquet du Faisan», qui comprend: la version contenue dans les Memoires d’Olivier de La Marche, celle de la Chronique de Mathieu d’Escouchy, celles des manuscrits Paris BnF fr. 11594, Paris BnF fr. 5739, Bruxelles BR IV.1103.
openaire   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Julian Barnes’s Flaubert’s Parrot and the Writerly Text

Critical Literary Studies
This paper examines Julian Barnes’s Flaubert’s Parrot by the five semiotic codes of the French literary critic Roland Barthes introduced in his renowned work S/Z, to show that the novel is a ‘writerly’ rather than a ‘readerly’ text.
Vali Gholami, Payam Babaie
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Concept of the five ′A′s for treating emergency arrhythmias

Journal of Emergencies, Trauma and Shock, 2010
Cardiac rhythm disturbances such as bradycardia (heart rate < 50/min) and tachycardia (heart rate > 100/min) require rapid therapeutic intervention.
Trappe Hans-Joachim
doaj  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Long-Term Impact of Pneumococcal Conjugate Vaccines on the Burden of Pneumococcal Meningitis in Mozambique, 2013–2023

Vaccines
Background: Mozambique introduced the 10-valent pneumococcal conjugate vaccine (PCV10) in 2013 using a three-dose primary series with no booster dose (3p+0) and later switched to the PCV13 using a schedule of two primary doses with one booster (2p+1). We
Aquino Albino Nhantumbo, Goitom Weldegebriel, Linda de Gouveia, Reggis Katsande, Charlotte Elizabeth Comé, Alcides Moniz Munguambe, Vlademir Cantarelli, Cícero Dias, Rachid Muleia, Ezequias Fenias Sitoe, Eunice Veronica Zeca, Amir Seni, Ana Nicolau Tambo, Ana Cristina de Faria Neves Mussagi, Plácida Iliany Maholela, Ivano de Filippis, Eduardo Samo Gudo   +16 more
doaj   +1 more source