Results 91 to 100 of about 4,109,256 (296)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Interaural time difference processing in the mammalian medial superior olive [PDF]

, 2008
The dominant cue for localization of low-frequency sounds are microsecond differences in the time-of-arrival of sounds at the two ears [interaural time difference (ITD)].
Behrend, Oliver, Brand, Antje, Grothe, Benedikt, Pecka, Michael   +3 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

The Case for a Muon Collider Higgs Factory

, 2013
We propose the construction of a compact Muon Collider Higgs Factory. Such a machine can produce up to \sim 14,000 at 8\times 10^{31} cm^-2 sec^-1 clean Higgs events per year, enabling the most precise possible measurement of the mass, width and Higgs ...
Alexahin, Yuri, Ankenbrandt, Charles M., Cline, David B., Conway, Alexander, Cummings, Mary Anne, Delahaye, Jean-Pierre, Di Benedetto, Vito, Eichten, Estia, Gatto, Corrado, Grinstein, Benjamin, Gunion, Jack, Han, Tao, Hanson, Gail, Hill, Christopher T., Ignatov, Fedor, Johnson, Rolland P., Lebedev, Valeri, Lederman, Leon M., Lipton, Ron, Liu, Zhen, Markiewicz, Tom, Mazzacane, Anna, Mokhov, Nikolai, Nagaitsev, Sergei, Neuffer, David, Palmer, Mark, Purohit, Milind V., Raja, Rajendran, Rubbia, Carlo, Striganov, Sergei, Summers, Don, Terentiev, Nikolai, Wenzel, Hans   +32 more
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The Cowl - v.2 - n.4 - Oct 23, 1936 [PDF]

, 1936
The Cowl - student newspaper of Providence College. Volume 2, Number 4 - Oct 23, 1936. 6 pages. Note: Due to the way these issues were bound into volumes, some of the letters on extreme left- and right-hand columns are slightly ...

core   +1 more source

Validation of Kepler's Multiple Planet Candidates. II: Refined Statistical Framework and Descriptions of Systems of Special Interest

, 2014
We extend the statistical analysis of Lissauer et al. (2012, ApJ 750, 112), which demonstrates that the overwhelming majority of Kepler candidate multiple transiting systems (multis) represent true transiting planets, and develop therefrom a procedure to
Agol, Eric, Borucki, William J., Bryson, Stephen T., Carter, Joshua A., Ford, Eric B., Gilliland, Ronald L., Jontof-Hutter, Daniel, Kolbl, Rea, Lissauer, Jack J., Marcy, Geoffrey W., Rowe, Jason F., Star, Kimberly M., Steffen, Jason H., Torres, Guillermo   +13 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Measuring interaction: An empirical comparison of three OLS regression models [PDF]

, 2008
The capacity to correctly assess the existence of interaction is a high-value modeling capability among researchers of information systems (IS), especially those focusing on behavioural paradigm studies.
Saleh Zolait, AZ, Sulaiman, A, Syed Alwi, SF   +2 more
core