Results 41 to 50 of about 37,375 (301)

Integrating Happiness Research into Endpoint Indicators of Social Life Cycle Analysis

open access: yesManaging Global Transitions
Endpoint indicators for social life cycle analysis (S-LCA) are still less consolidated than those for environmental LCA. There is a broad consensus that human well-being should be the overarching goal of social sustainability and therefore also of S-LCA.
Stefan Mann, Melf-Hinrich Ehlers
doaj   +1 more source

Estimation of heterosis for earliness, yield and yield attributing traits in chilli (Capsicum annuum L.)

open access: yesElectronic Journal of Plant Breeding, 2018
The present investigation was carried out to estimate the magnitude of heterosis over mid parent, better parent and standard checks (Tejaswini and Indam-5) for earliness, fruit yield and yield attributing traits in chilli (Capsicum annuum L.) and ...
M. Janaki   +5 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Education in 'life cycle sustainability assessment': caring for all 3 P's in one [PDF]

open access: yes, 2013
Starting from the observation that externalities, reflecting societal concerns, emerge from costs and benefits which are not reflected in the market price, the authors of the paper emphasize the importance in education of life cycle sustainability ...
Ciroth, Andreas   +3 more
core  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Hospital Readmission After Traumatic Brain Injury Hospitalization in Community‐Dwelling Older Adults

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the risk of hospital readmission after an index hospitalization for TBI in older adults. Methods Using data from the Atherosclerosis Risk in Communities (ARIC) study, we used propensity score matching of individuals with an index TBI‐related hospitalization to individuals with (1) non‐TBI hospitalizations (primary analysis)
Rachel Thomas   +7 more
wiley   +1 more source

microRNA-139-3p Inhibits Malignant Behaviors of Laryngeal Cancer Cells via the KDM5B/SOX2 Axis and the Wnt/β-Catenin Pathway

open access: yesCancer Management and Research, 2020
Yifei Ma,1,2,* Zili Chen,3,* Guodong Yu2 1School of Clinical Medicine, Guizhou Medical University, Guiyang 550004, Guizhou, People’s Republic of China; 2Department of Otorhinolaryngology, Affiliated Hospital of Guizhou Medical University, Guiyang ...
Ma Y, Chen Z, Yu G
doaj  

Participation in S-LCA: A Methodological Proposal Applied to Belgian Alternative Food Chains (Part 1)

open access: yesResources, 2019
In social life cycle assessment (S-LCA), the use of a participatory approach to define and select assessment criteria and indicators (C&Is) is recommended given the specificity of social issues, but it has been, for now, rarely implemented and ...
Solène Sureau   +4 more
doaj   +1 more source

Using life cycle sustainability assessment to trade off sourcing strategies for humanitarian relief items [PDF]

open access: yes, 2016
Purpose: While interest in supply chain sustainability has risen over the past few years in academic and business worlds, very little research has been conducted on sustainability in humanitarian supply chains, specifically. This study aims to contribute
De Leeuw, S   +3 more
core   +2 more sources

Cumulative Social Disadvantage and Disease Activity in Juvenile Idiopathic Arthritis: A Childhood Arthritis and Rheumatology Research Alliance Registry Study

open access: yesArthritis Care &Research, EarlyView.
Objective Social determinants of health (SDOH) contribute to juvenile idiopathic arthritis (JIA) disparities, but most studies have assessed SDOH independently rather than cumulatively across individual, family, and neighborhood levels. Using a socioecological framework, we investigated the relationship among cumulative social disadvantage ...
William Daniel Soulsby   +448 more
wiley   +1 more source

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