Results 71 to 80 of about 5,622 (217)

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Bias within economic evaluations – the impact of considering the future entry of lower-cost generics on currently estimated incremental cost-effectiveness ratios of a new drug

ClinicoEconomics and Outcomes Research, 2015
Jason R Guertin,1,2 Dominic Mitchell,1,3 Farzad Ali,4 Jacques LeLorier1 1CHUM Research Center, Montréal, QC, 2Programs for Assessment of Health Technology in Health Research Institute, Hamilton, ON, 3Logimétrix Inc., Repentigny, 4Pfizer ...
Guertin JR, Mitchell D, Ali F, LeLorier J   +3 more
doaj  

Underwater Sound Speed Field Forecasting Based on the Least Square Support Vector Machine

Journal of Marine Science and Engineering
Underwater sound speed is one of the most significant factors that affects high-accuracy underwater acoustic positioning and navigation. Due to its complex temporal variation, the forecasting of the underwater sound speed field (SSF) becomes a ...
Junting Wang, Tianhe Xu, Wei Huang, Liping Zhang, Jianxu Shu, Yangfan Liu, Linyang Li   +6 more
doaj   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Characterization and modeling of high frequency equivalent noise in GFET based on contact resistance

四川大学学报. 自然科学版
A small signal equivalent circuit model of Graphene Field Effect Transistors （GFET） is proposed， which takes into account the internal physical transmission phenomenon of metal-graphene interface， namely the contact resistance between drain and source.A
LI Rui, WANG Jun
doaj  

Observational constraints on a nonlinear spinor field quintessence model in an FLRW universe

European Physical Journal C: Particles and Fields
In the framework of a spherically symmetric Friedmann–Lemaître–Robertson–Walker (FLRW) spacetime, we construct a quintessence model driven by a nonlinear, massless spinor field in an open-universe scenario.
Mahendra Goray, Bijan Saha
doaj   +1 more source

Full-grid bathymetry estimation in the numerical simulation of 8 tidal constituents using an ensemble adjustment Kalman filter-smoothing scheme

Frontiers in Marine Science
The spatially varying geographic-parameters introduce significant uncertainty into the ocean model. Due to the impracticality of manually tuning spatial varying parameters, data assimilation methods are widely used for geographic-parameter optimization ...
Haowen Wu, Haowen Wu, Wei Li, Wei Li, Wei Li, Guijun Han, Guijun Han, Lige Cao, Lige Cao, Xudong Cui, Xudong Cui, Kangzhuang Liang, Kangzhuang Liang, Gongfu Zhou, Gongfu Zhou, Qingyu Zheng, Qingyu Zheng   +16 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source