Results 51 to 60 of about 358,280 (266)

Pixel-MPS: Stochastic Embedding and Density-Based Clustering of Image Patterns for Pixel-Based Multiple-Point Geostatistical Simulation

Geosciences
Multiple-point geostatistics (MPS) is an established tool for the uncertainty quantification of Earth systems modeling, particularly when dealing with the complexity and heterogeneity of geological data. This study presents a novel pixel-based MPS method
Adel Asadi, Snehamoy Chatterjee
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Performance Comparison of Metaheuristic Optimization-Based Parametric Methods in Wind Turbine Power Curve Modeling

IEEE Access
Wind-based power generation, which is a safe and clean energy resource, has a widespread implementation around the world to reduce the environmental pollution, alleviate the energy crisis and provide the economic benefits.
Mehmet Yesilbudak, Ahmet Ozcan
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Research on PFC3D meso-parameters prediction model and strength simulation of backfill based on hemical-mechanical coupling

Scientific Reports
This study develops and validates a meso-parameter prediction model for backfill materials in PFC3D, enabling efficient numerical construction under varying curing ages and mix ratios.
Yong Wang, Chen Cao, Defeng Wang, Jiang Jiao, Aixiang Wu   +4 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Determination of the controlling resistance to moisture transfer during drying

Croatian Journal of Food Science and Technology, 2012
In this study the correlation between lag factor G and Page´s mathematical model parameter n was developed. Using the newly developed correlation the presence of internal or external resistance to moisture transfer during thermal drying can be verified ...
T. Jurendić
doaj  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Parameters Estimation of Proton Exchange Membrane Fuel Cell Model Based on an Improved Walrus Optimization Algorithm

IEEE Access
Proton Exchange Membrane Fuel Cells (PEMFCs) play a crucial role in the advancement of clean hydrogen vehicles. Their ability to convert hydrogen into electricity makes them promising candidates to replace conventional engines.
Ayedh H. Alqahtani, Hany M. Hasanien, Mohammed Alharbi, Sun Chuanyu   +3 more
doaj   +1 more source