MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
F089 Mitochondrial parameters in peripheral tissues in early stages of Huntington´s disease [PDF]
Hana Hansíková +8 more
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Research on a Degradation Identification Method for GIS UHF Partial Discharge Sensors Based on S-Parameters. [PDF]
Sensors (Basel)Cao T +7 more
europepmc +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Rectenna System Development Using Harmonic Balance and S-Parameters for an RF Energy Harvester. [PDF]
Sensors (Basel)Md Jamil MNB +5 more
europepmc +1 more source
IMPROVED EXTRACTION OF COUPLING MATRIX AND UNLOADED Q FROM S-PARAMETERS OF LOSSY RESONATOR FILTERS
, 2011 Rui Wang +4 more
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Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Analytic Continuation, Phase Unwrapping, and Retrieval of the Refractive Index of Metamaterials from S-Parameters. [PDF]
Sensors (Basel)Angiulli G +3 more
europepmc +1 more source
Parameters of the backbone structures of D2FLS-Net -L, D2FLS-Net -B and D2FLS-Net -S.
Chengwei Zhao (5039315) +7 more
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