Results 221 to 230 of about 301,171 (270)

EGR Proteins Mediate Interferon‐Independent Anti‐HSV‐1 Responses Through Viral and Host Targets

Advanced Science, EarlyView.
Early antiviral responses are typically mediated by interferons. However, during HSV‐1 infection, host early growth response (Egr) genes, which are not interferon‐stimulated genes, are quickly induced by viral protein ICP0. EGR proteins, in turn, suppress viral lytic infection by activating viral latency‐associated (LAT) and host immune regulatory ...
Shuaishuai Wang, Fujun Hou, Xunuo Jin, Yuhang Xiang, Dongli Pan   +4 more
wiley   +1 more source

2'-hydroxyl modification improves enzymatic and thermal stability of mRNA. [PDF]

Mol Ther Nucleic Acids
Uchida S.
europepmc   +1 more source

Preliminary characterization of the self-incompatibility genotypes of European plum (Prunus domestica L.) cultivars. [PDF]

, 2014
Halász, Júlia, Hegedűs, Attila, Kurilla, Anita   +2 more
core  

IL‐4/STAT6‐signaling Influences Local Inflammation and Regeneration Processes During Acute Pancreatitis and Promotes Fibrosis by a Direct Activation of Pancreatic Fibroblasts During Chronic Pancreatitis

Advanced Science, EarlyView.
IL‐4/IL‐13/STAT6 signaling plays a crucial for the suppression of pro‐inflammation during acute pancreatitis and supports acinar cell regeneration but has only minor impact on fibrogenesis during chronic form of the disease. IL‐4/IL‐13 induce the expression of certain collagens directly in pancreatic fibroblasts via STAT6 activation, whereas ...
ElSheikh H, Salvers A, Piesker J, Buchholz S, Lange R, Ameling S, Steil L, Hammer E, Homuth G, Völker U, Bröker BM, Weiss FU, Sendler M, Glaubitz J   +13 more
wiley   +1 more source

The HigB-like SehA toxin promotes non-replicating Salmonella inside macrophages by inhibiting ribonuclease III-dependent rRNA maturation. [PDF]

Nucleic Acids Res
Choi S, Cho YJ, Baek S, Choi E, Kim YK, Choi TS, Lee EJ.   +6 more
europepmc   +1 more source

Self-incompatibility system in polyploid fruit tree species- A review [PDF]

, 2016
Halász, Júlia, Makovics-Zsohár, Noémi   +1 more
core  

Halorotetin B, A Novel Terpenoid Compound Derived from Marine Ascidian, Suppresses Tumor Growth by Targeting the Cell Cycle Regulator UBE2C

Advanced Science, EarlyView.
Halorotetin B, a novel small‐molecule terpenoid identified from an edible marine ascidian, exhibits strong anti‐tumor activity both in vitro and in vivo through direct targeting UBE2C to induce tumor cell cycle arrest and then lead tumor cell senescence. As a newly discovered UBE2C inhibitor, Halorotetin B can serve as a novel potential cell senescence
Shanhao Han, Jianhui Li, Yuting Zhu, Penghui Liu, Yaoyao Zheng, Muchun He, Bo Dong   +6 more
wiley   +1 more source

Cleavage of host tRNAs by mycoplasma membrane-associated nuclease. [PDF]

Nucleic Acids Res
Akiyama Y, Takenaka Y, Kunii N, Aoyama K, Yamada A, Abe T, Tomioka Y, Ivanov P.   +7 more
europepmc   +1 more source

TP53BP2 Promotes Placental Autophagy and Preeclampsia via G9a and DNMT1 Cooperatively Modulating E2F1

Advanced Science, EarlyView.
G9a, and DNA Methyltransferase1 (DNMT1) cooperatively modulates E2F1 on the promoter of tumor suppressor p53‐binding protein 2 (TP53BP2) increased autophagy in preeclampsia. TP53BP2 promotes autophagy in trophoblasts through DNA methylation and H3K9me2‐mediated transcriptional regulation.
Nan Jiang, Shaoju Jin, Shaoying Wen, Wen Zeng, Chen Wang, Jingyu Wang, Qingyun Song, Guizhong Li, Pengzhi Yin, Yuhui Liao, Yuee Chai, Huiping Zhang, Shengchao Ma   +12 more
wiley   +1 more source

<i>Sinorhizobium meliloti</i> BR-bodies promote fitness during host colonization. [PDF]

mBio
Mallikaarachchi KS, Huang JL, Madras S, Cuellar RA, Huang Z, Gega A, Rathnayaka-Mudiyanselage IW, Nandana V, Al-Husini N, Saldaña-Rivera N, Ma LH, Ng E, Christensen K, Pendar N, Li S, Deleon NR, Chen JC, Schrader JM.   +17 more
europepmc   +1 more source