Results 241 to 250 of about 301,171 (270)

Calcium Channel Blockers Inhibit Pancreatic Neuroendocrine Neoplasms Progression via Cav1.2‐Epigenetic Circuit

Advanced Science, EarlyView.
Our study reveals a novel mechanism of a positive regulatory circuit between Cav1.2 and H3K27ac for pancreatic neuroendocrine neoplasms (pNENs) progression. Cav1.2 is identified as a crucial target for promoting disease progression and correlates with malignant behaviors, which are remarkably inhibited by the administration of calcium channel blockers (
Yangyinhui Yu, Qiongcong Xu, Jinzhao Xie, Mingjian Ma, Xitai Huang, Yinhao Shi, Jiawei Zhou, Enliang Zhu, Ziyi Zhao, Ning Zhang, Zhide Liu, Jingyuan Ye, Xiaoyu Yin   +12 more
wiley   +1 more source

Ultrasound Controlled‐Release Hydrogel Promotes Diabetic Wound Healing via Neuroimmune Modulation and Synergistic ROS Scavenging

Advanced Science, EarlyView.
This study presents an ultrasound‐responsive hydrogel (MCF@CA) that co‐delivers a neuropeptide (CGRP) and a ROS‐scavenging manganese porphyrin to diabetic wounds. The system restores neuro‐immune communication, reprograms macrophages toward an anti‐inflammatory phenotype, and clears excess ROS, thereby accelerating wound closure and promoting mature ...
Mofan Li, Mengxin Wang, Haonan Wang, Yang Sun, Yongyue Zhang, Shuyu Xu, Tianjiao Zhang, Shiti Shama, Xiaolong Liang, Shumin Wang   +9 more
wiley   +1 more source

Effects of ribonucleotides on telomeric G4 formation, dynamics, and initiation of ribonucleotide excision repair by RNase H2. [PDF]

Nucleic Acids Res
Cortez LM, Rahman MIR, Welfer GA, Riva F, Buettner KJ, Lee HT, Freudenthal BD.   +6 more
europepmc   +1 more source

How much genetic information in RNA form can be protected by a CCMV virus-like particle? [PDF]

PLoS One
Duran Meza AL, Porak SC, Chapman A, Knobler CM, Gelbart WM.   +4 more
europepmc   +1 more source

The Poetry of Reproduction: Beverley Glover, Understanding Flowers and Flowering. An Integrated Approach, 2007, Oxford University Press, x+227pp, £XX, ISBN: 978-0-19-856597-0 [PDF]

, 2018
Hennig, Lars
core  

Pan-S-locus analysis reveals insights into the origin and evolution of self-incompatibility in the orange subfamily. [PDF]

Genome Biol
Hu J, Du Z, Liu C, Wen H, Liu C, Chen P, Shi C, Ye J, Ji Q, Deng X, Bosch M, Lin Z, Jiao WB, Chai L.   +13 more
europepmc   +1 more source

Interplay Between DNA Polymerase, RNA Polymerase, and RNase H1 During Head-On Transcription-Replication Conflict. [PDF]

Int J Mol Sci
Timofeyeva NA, Tsoi EI, Novopashina DS, Kuznetsov NA, Kuznetsova AA.   +4 more
europepmc   +1 more source

RNase MRP subunit composition and role in 40S ribosome biogenesis. [PDF]

Nat Struct Mol Biol
Smith EM, Ly J, Haug S, Cheeseman IM.
europepmc   +1 more source

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A mutation near the active site of S-RNase causes self-compatibility in S-RNase-based self-incompatible plants

Plant Molecular Biology, 2020
The structurally simplest amino acid glycine could make contribution to nuclease activity of S-RNase and self-incompatibility in S-RNase-based plants. S-RNase is regarded as inhibitor of self-pollen tube in S-RNase-based self-incompatibility plants. Certain residues like histidine are necessary for RNase activity and self-incompatibility; however, it ...
Yang Li, Junkai Wu, Chuanbao Wu, Jie Yu, Chunsheng Liu, Wenqi Fan, Tianzhong Li, Wei Li   +7 more
openaire   +2 more sources