Global network analysis of drug tolerance, mode of action and virulence in methicillin-resistant S. aureus [PDF]
, 2011 Background: Staphylococcus aureus is a major human pathogen and strains resistant to existing treatments continue to emerge. Development of novel treatments is therefore important.
Barton, Geoffrey J +30 more
core +1 more source
Staphylococcus aureus temperate bacteriophage: carriage and horizontal gene transfer is lineage associated. [PDF]
, 2012 Staphylococcus aureus is a major cause of human and animal infections. Bacteriophage are a class of mobile genetic element (MGE) that carry virulence genes and disseminate them horizontally, including Panton-Valentine leukocidin (PVL), the immune evasion
McCarthy, AJ +8 more
core +1 more source
The management of Staphylococcus aureus bacteremia in the United Kingdom and Vietnam: a multi-centre evaluation. [PDF]
, 2010 BACKGROUND: Staphylococcus aureus bacteremia is a common and serious infection worldwide and although treatment guidelines exist, there is little consensus on optimal management.
Jonathan Edgeworth (471617) +23 more
core +1 more source
The distribution of plasmids that carry virulence and resistance genes in Staphylococcus aureus is lineage associated. [PDF]
, 2012 BACKGROUND: Staphylococcus aureus is major human and animal pathogen. Plasmids often carry resistance genes and virulence genes that can disseminate through S. aureus populations by horizontal gene transfer (HGT) mechanisms. Sequences of S.
McCarthy, AJ +5 more
core +1 more source
Staphylococcus aureus lipoproteins - TLR2-mediated activation of innate and adaptive immunity [PDF]
, 2010 Staphylococcus (S.) aureus is a very successful pathogen due to its immune evasion strategies. Besides toxins and adhesins, it expresses membrane lipoproteins (Lpp), which are bound by the pattern recognition receptor Toll-like receptor (TLR) 2 in the ...
Schmaler, Mathias
core +1 more source
Living with an imperfect cell wall: compensation of femAB inactivation in Staphylococcus aureus [PDF]
, 2007 Background: Synthesis of the Staphylococcus aureus peptidoglycan pentaglycine interpeptide bridge is catalyzed by the nonribosomal peptidyl transferases FemX, FemA and FemB.
Majcherczyk, Paul A +39 more
core +3 more sources
Rapid PCR Detection of Staphylococcus aureus Clonal Complex 398 by Targeting the Restriction-Modification System Carrying sau1-hsdS1 [PDF]
, 2011 A PCR targeting sau1-hsdS1 was developed for rapid detection of Staphylococcus aureus clonal complex 398 (CC398). High sensitivity (100%) and specificity (100%) were shown by evaluating the test on a large strain collection (n = 1,307). We recommend this
Broens, Els M. +17 more
core +1 more source
Heterogeneity in ess transcriptional organization and variable contribution of the Ess/Type VII protein secretion system to virulence across closely related Staphylocccus aureus strains [PDF]
, 2014 The Type VII protein secretion system, found in Gram-positive bacteria, secretes small proteins, containing a conserved W-x-G amino acid sequence motif, to the growth medium.
Chalmers, James +16 more
core +2 more sources
Difference in virulence between Staphylococcus aureus isolates causing gangrenous mastitis versus subclinical mastitis in a dairy sheep flock [PDF]
, 2009 Staphylococcus aureus mastitis in dairy sheep ranges from subclinical mastitis to lethal gangrenous mastitis. Neither the S. aureus virulence factors nor the host-factors or the epidemiological events contributing to the different outcomes are known.
Le Loir, Y +23 more
core +1 more source
Surveillance for S aureus bacteraemias is compulsory
BMJ, 2002 EDITOR—Van Belkum and Verbrugh's editorial on methicillin resistant Staphylococcus aureus (MRSA) focused on the Dutch experience.1 It was England that first detected methicillin resistance in S aureus ,2 and despite the apparent disappearance of these strains in the United Kingdom in the 1970s their descendants are causing problems now.
Georgia, Duckworth +3 more
openaire +3 more sources