Results 11 to 20 of about 382,867 (264)

Global network analysis of drug tolerance, mode of action and virulence in methicillin-resistant S. aureus [PDF]

, 2011
Background: Staphylococcus aureus is a major human pathogen and strains resistant to existing treatments continue to emerge. Development of novel treatments is therefore important.
Barton, Geoffrey J, Peter J Coote, Botting, Catherine H., Katherine A Gould, Geoffrey J Barton, Hinds, Jason, Overton, Ian M., Gould, Katherine A., Coote, Peter J, Gould, Katherine A, Shirran, Sally, Botting, CH, Catherine H Botting, Barton, GJ, Coote, Peter J., Gould, KA, Shirley Graham, Botting, Catherine H, Overton, IM, Ian M Overton, Overton, Ian M, Barton, Geoffrey J., Graham, Shirley, Shirran, S, Overton, Ian M; id_orcid, Hinds, J, Sally Shirran, Coote, PJ, Jason Hinds, Barton, Geoffrey J.; id_orcid, Graham, S   +30 more
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Staphylococcus aureus temperate bacteriophage: carriage and horizontal gene transfer is lineage associated. [PDF]

, 2012
Staphylococcus aureus is a major cause of human and animal infections. Bacteriophage are a class of mobile genetic element (MGE) that carry virulence genes and disseminate them horizontally, including Panton-Valentine leukocidin (PVL), the immune evasion
McCarthy, AJ, Lindsay, JA, Alex J Mccarthy, Jodi A Lindsay, Witney, AA, Adam A Witney, Alex J. McCarthy, Jodi. A. Lindsay, Adam A. Witney   +8 more
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The distribution of plasmids that carry virulence and resistance genes in Staphylococcus aureus is lineage associated. [PDF]

, 2012
BACKGROUND: Staphylococcus aureus is major human and animal pathogen. Plasmids often carry resistance genes and virulence genes that can disseminate through S. aureus populations by horizontal gene transfer (HGT) mechanisms. Sequences of S.
McCarthy, AJ, Lindsay Jodi A, Lindsay, JA, Jodi A Lindsay, McCarthy Alex J, Alex J McCarthy   +5 more
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The management of Staphylococcus aureus bacteremia in the United Kingdom and Vietnam: a multi-centre evaluation. [PDF]

, 2010
BACKGROUND: Staphylococcus aureus bacteremia is a common and serious infection worldwide and although treatment guidelines exist, there is little consensus on optimal management.
Jonathan Edgeworth (471617), Peter Wilson (132656), Thwaites Guy E., Andrew Kirby (47075), Guy E Thwaites, John Klein (8885316), Heiman F.L. Wertheim (16049003), Sarah Walker (122261), United Kingdom Clinical Infection Research Group (UKCIRG), Robert Tilley (15893375), Matthew Scarborough (328340), null null, Thwaites, Guy E., Ho Dang Trung Nghia (16048997), M. Estée Török (16049000), James Whitehorn (155594), Guy E. Thwaites, Thwaites, GE, Trinh Duong (311438), Thwaites, Guy E, Susan Hopkins (458187), Guy E. Thwaites (8407644), Chanaka de Silva (16048994), Martin Llewelyn (4461757)   +23 more
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Evolutionary Genomics of Staphylococcus aureus Reveals Insights into the Origin and Molecular Basis of Ruminant Host Adaptation [PDF]

, 2010
Phenotypic biotyping has traditionally been used to differentiate bacteria occupying distinct ecological niches such as host species. For example, the capacity of Staphylococcus aureus from sheep to coagulate ruminant plasma, reported over 60 years ago ...
Fitzgerald J.R., Smyth, D.S., Jodi A. Lindsay, Lindsay, J.A., Hinds, Jason, Davida S. Smyth, Tormo-Mas, Maria A, Gould, Katherine A, Jonathan P. Bollback, Rambaut, A, Ben Zakour, N.L., Cyril J Smyth, Fitzgerald, Ross; id_orcid, Lowder, Bethan V., Hinds J., Penades, Jose R, J Ross Fitzgerald, Witney, A., Rambaut A., Katherine A. Gould, Hinds, J, Bollback, J.P., Jason Hinds, J. Ross Fitzgerald, Tormo-Mas, María A., Smyth D.S., Nouri L Ben Zakour, Penades J.R., Jonathan P Bollback, Weinert, Lucy A, Caitriona M. Guinane, Nouri L. Ben Zakour, Bethan V Lowder, Smyth, Davida S, Davida S Smyth, Gould, KA, Guinane, C.M., Rambaut, A., Lowder B.V., Lowder, BV, Cartwright, R.A., Fitzgerald, J. Ross, Lindsay, Jodi A, Cyril J. Smyth, Cartwright R.A., Tormo-Mas, MA, Ben Zakour, Nouri L., Weinert, LA, Tormo-Mas, M.A., Gould, Katherine A., Maria A. Tormo-Mas, Caitriona M Guinane, Penades, JR, Smyth, Cyril J., Gould, K.A., Smyth, C.J., Smyth, Cyril J, Cartwright, RA, Lucy A. Weinert, Fitzgerald, JR, Penades, J.R., Cartwright, Robyn, Bethan V. Lowder, Ben Zakour, NL, Lindsay, JA, Smyth C.J., Andrew Rambaut, Gould K.A., Jodi A Lindsay, Weinert, Lucy A., Guinane, Caitriona M., Witney, Adam, Bollback J.P., Hinds, J., Bollback, Jonathan P., Lowder, Bethan V, Guinane, CM, Katherine A Gould, Witney, A, Guinane C.M., Lowder, B.V., Weinert L.A., Lindsay J.A., Robyn A. Cartwright, Tormo-Mas M.A., Maria A Tormo-Mas, Lindsay, Jodi A., Smyth, DS, Weinert, L.A., Bollback, Jonathan P, Lucy A Weinert, Ben Zakour, Nouri L, Bollback, JP, Witney A., Rambaut, Andrew, Penadés, José R., Smyth, CJ, Zakour N.L.B., José R Penadé S, Guinane, Caitriona M, Fitzgerald, J.R., Cartwright, Robyn A, Fitzgerald, J Ross, Adam Witney, Cartwright, Robyn A., Robyn A Cartwright, José R. Penadés   +106 more
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Difference in virulence between Staphylococcus aureus isolates causing gangrenous mastitis versus subclinical mastitis in a dairy sheep flock [PDF]

, 2009
Staphylococcus aureus mastitis in dairy sheep ranges from subclinical mastitis to lethal gangrenous mastitis. Neither the S. aureus virulence factors nor the host-factors or the epidemiological events contributing to the different outcomes are known.
Le Loir, Y, Robinson, DA, Caroline Le Marechal, Vautor, Eric, Le Loir, Yves, Lindsay, Jodi, Le Marechal, C, Lindsay, J, Joshua Cockfield, D. Ashley Robinson, Chevalier, M, Le Marechal, Caroline, Jodi Lindsay, Chevalier, Marlène, Vautor, E, Richard Thiery, Eric Vautor, Thiery, R, Cockfield, J, Cockfield, Joshua, Yves Le Loir, Marlène Chevalier, Robinson, D., Thiery, Richard   +23 more
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Staphylococcus aureus lipoproteins - TLR2-mediated activation of innate and adaptive immunity [PDF]

, 2010
Staphylococcus (S.) aureus is a very successful pathogen due to its immune evasion strategies. Besides toxins and adhesins, it expresses membrane lipoproteins (Lpp), which are bound by the pattern recognition receptor Toll-like receptor (TLR) 2 in the ...
Schmaler, Mathias
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Rapid PCR Detection of Staphylococcus aureus Clonal Complex 398 by Targeting the Restriction-Modification System Carrying sau1-hsdS1 [PDF]

, 2011
A PCR targeting sau1-hsdS1 was developed for rapid detection of Staphylococcus aureus clonal complex 398 (CC398). High sensitivity (100%) and specificity (100%) were shown by evaluating the test on a large strain collection (n = 1,307). We recommend this
Broens, Els M., Moodley, Arshnee, Guardabassi, L., Marc Stegger, Jodi A. Lindsay, Arshnee Moodley, Lindsay, J.A., Stegger, Marc, Broens, E.M., Els M. Broens, Skov, Robert, Moodley, A., Lindsay, Jodi A., Guardabassi, Luca, Skov, R., Robert Skov, Stegger, M., Luca Guardabassi   +17 more
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Heterogeneity in ess transcriptional organization and variable contribution of the Ess/Type VII protein secretion system to virulence across closely related Staphylocccus aureus strains [PDF]

, 2014
The Type VII protein secretion system, found in Gram-positive bacteria, secretes small proteins, containing a conserved W-x-G amino acid sequence motif, to the growth medium.
Chalmers, James, Jäger, Franziska, van der Kooi - Pol, Magda, Cargill, James S, Cao, Zhen Ping, van der Kooi-Pol, Magdalena M., Hunter, William N., Palmer, Tracy, Ryan, Robert P., Kneuper, Holger, Twomey, Kate B., Ryan, Robert P, Zoltner, Martin, Twomey, Kate B, Cargill, James S., van Dijl, Jan Maarten, Hunter, William N   +16 more
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Extensive horizontal gene transfer during Staphylococcus aureus co-colonization in vivo. [PDF]

, 2014
Staphylococcus aureus is a commensal and major pathogen of humans and animals. Comparative genomics of S. aureus populations suggests that colonization of different host species is associated with carriage of mobile genetic elements (MGE), particularly ...
McCarthy, AJ, Lloyd, DH, Lindsay, JA, Lindsay, J A, Gould, K A, Witney, AA, Gould, KA, Loeffler, A, Witney, A A, McCarthy, A J, Lloyd, D H   +10 more
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