Results 121 to 130 of about 20,287,569 (319)

Porin‐Independent Uptake of Small Molecule Antibiotics Facilitated by Escherichia coli Outer Membrane Vesicles

open access: yesBiotechnology and Bioengineering, EarlyView.
We demonstrate that bacterial outer membrane vesicles (OMVs) can enhance antibiotic delivery into Gram‐negative bacteria by bypassing porin‐dependent uptake. Encapsulation of imipenem in OMVs significantly increased its effectiveness against multidrug‐resistant clinical isolates, highlighting OMVs as a promising platform for overcoming permeability ...
Meishan Wu   +3 more
wiley   +1 more source

National survey of colistin resistance among carbapenemase-producing Enterobacteriaceae and outbreak caused by colistin-resistant OXA-48-producing Klebsiella pneumoniae, France, 2014 [PDF]

open access: yes, 2016
From January 2014 to December 2014, 972 consecutive non-replicate carbapenemase-producing Enterobacteriaceae isolates from colonised or infected patients were collected at the Associated French National Reference Centre as part of the French national ...
Dortet, L   +3 more
core   +1 more source

Mathematical Modeling of Amoxicillin Synthesis in Batch and Semi‐Batch Reactor: Application of Bayesian Statistics and Genetic Algorithm

open access: yesBiotechnology and Bioengineering, EarlyView.
Synthesis of amoxicillin: The reaction catalyzed by penicillin G acylase is investigated in an enzymatic reactor, considering both Michaelis–Menten and mechanism‐based models with reaction and equilibrium constants. Parameters are estimated via MCMC and Genetic Algorithm, with MCMC showing superior performance in validating the mathematical model in a ...
Lucas Figueiredo Formigosa   +5 more
wiley   +1 more source

Evaluation of the Blue-Carba test for rapid detection of carbapenemases in gram-negative Bacilli [PDF]

open access: yes, 2015
The Blue-Carba test (BCT) is a biochemical test for rapid (2 h)detection of carbapenemase production in Gram-negative bacillidirectly from bacterial culture .
Albornoz, Ezequiel Pablo   +7 more
core   +1 more source

A Promising Antibacterial Inhibition of Propolis Extracts Against Carbapenem‐Resistant Bacteria Isolated From Clinical Samples

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT The increasing inadequacy of antibiotics against multidrug‐resistant pathogens is a growing concern. In this study, the antibacterial activity of propolis extracts with different phenolic profiles against carbapenem‐resistant clinical isolates was investigated.
Ülkü Zeynep Esertaş   +3 more
wiley   +1 more source

Population genomics of hypervirulent Klebsiella pneumoniae clonal-group 23 reveals early emergence and rapid global dissemination

open access: yesNature Communications, 2017
Severe liver abscess infections caused by hypervirulent clonal-group CG23 Klebsiella pneumoniae have been increasingly reported since the mid-1980s. Strains typically possess several virulence factors including an integrative, conjugative element ICEKp ...
M. Lam   +13 more
semanticscholar   +1 more source

Reactivity of Carbohydrate Phosphodiesters, Potential Targets of Antibacterial Agents

open access: yesChemistry &Biodiversity, EarlyView.
A simple carbohydrate phosphodiester model was synthesized to compare the reactivity of phosphodiester bonds within carbohydrates and RNA. ABSTRACT While monosaccharide units in bacterial carbohydrates may be linked with phosphodiester bonds, human carbohydrates exclusively contain glycosidic linkages.
Eero Sillanpää   +2 more
wiley   +1 more source

PERBANDINGAN PERTUMBUHAN Streptococcus pneumoniae PADA MEDIA AGAR DARAH DOMBA MENGGUNAKAN TRYPTICASE SOY AGAR DENGAN COLUMBIA AGAR [PDF]

open access: yes, 2018
Latar Belakang Columbia agar dengan suplementasi darah domba merupakan agar yang banyak digunakan sebagai media kultur S. pneumoniae. Namun kegagalan untuk menumbuhkan S.
Farida, Helmia   +2 more
core  

Bacterial Infection Elicits Heat Shock Protein 72 Release from Pleural Mesothelial Cells [PDF]

open access: yes, 2013
Heat shock protein 70 (HSP70) has been implicated in infection-related processes and has been found in body fluids during infection. This study aimed to determine whether pleural mesothelial cells release HSP70 in response to bacterial infection in vitro
Bielsa, S   +8 more
core   +1 more source

Potential of Eugenia brejoensis (Mazine) Essential Oil in Combating Multidrug‐Resistant (MDR) Acinetobacter baumannii and Pseudomonas aeruginosa

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT The genus Eugenia has a long history of use in traditional medicine for treating various conditions, including infectious diseases, gastrointestinal disorders, and skin problems. Essential oils derived from Eugenia species are known for their medicinal properties and have been studied for their antimicrobial and bioactive potential. This study
Jonathan Mandú de Araújo   +10 more
wiley   +1 more source

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