Integrated immunoinformatics and subtractive proteomics approach for multi-epitope vaccine designing to combat S. pneumoniae TIGR4. [PDF]
Ashgar SS +7 more
europepmc +1 more source
The power of many: when genetics met yeasts and high‐throughput
ABSTRACT In recent years, complex technological capabilities have evolved, driven by the need to solve complex and integrative biological questions through global analyses. New equipment allows the scaling up and automation of processes which previously were carried out on a very limited scale.
Víctor A. Tallada, Víctor Carranco
wiley +1 more source
Phylogenomic insights into evolutionary trajectories of multidrug resistant S. pneumoniae CC271 over a period of 14 years in China. [PDF]
Zeng Y +12 more
europepmc +1 more source
Phr‐peptide signaling by S. pneumoniae
The Phr peptides of the Bacillus species mediate quorum sensing, but their identification and function in other species of bacteria have not been determined. We have identified a Phr peptide quorum-sensing system (TprA/PhrA) that controls the expression of a lantibiotic gene cluster in the Gram-positive human pathogen, Streptococcus pneumoniae ...
Hoover, Sharon E +7 more
openaire +2 more sources
Pore-forming activity of S. pneumoniae pneumolysin disrupts the paracellular localization of the epithelial adherens junction protein E-cadherin. [PDF]
Xu S +8 more
europepmc +1 more source
Abstract Background Based on human studies, surgical antimicrobial (AMD) prophylaxis (SAP) beyond 24 h is unnecessary and potentially detrimental. Objective To compare clinical and microbiological outcomes in patients receiving 24‐ or 72‐h of SAP for colic surgery. Study Design Prospective randomised clinical trial.
Louise L. Southwood +6 more
wiley +1 more source
StkP- and PhpP-Mediated Posttranslational Modifications Modulate the S. pneumoniae Metabolism, Polysaccharide Capsule, and Virulence. [PDF]
Kant S, Sun Y, Pancholi V.
europepmc +1 more source
Perbedaan Pola Kepekaan Terhadap Antibiotik Pada Streptococcus Pneumoniae Yang Mengkolonisasi Nasofaring Balita [PDF]
Latar Belakang: S. pneumoniae merupakan salah satu penyebab utama terjadinya pneumonia. Kolonisasi S. pneumoniae terdapat pada saluran pernapasan.S. pneumoniae di nasofaring banyak dijumpai pada anak.
Farida, H. (Helmia) +2 more
core
Advances in Double‐Stranded DNA Targeting Technologies
Double‐stranded DNA (dsDNA) plays a crucial role in genetic information storage and disease management, but its inherent stability limits access to internal bases. To overcome this challenge, various high‐specificity molecular targeting technologies have been developed to destabilize the DNA structure.
Zuhao Shen +8 more
wiley +1 more source
Exploration of Streptococcus core genome to reveal druggable targets and novel therapeutics against S. pneumoniae. [PDF]
Chowdhury ZM +8 more
europepmc +1 more source

