Host responses to S. pneumoniae in wild type and Mertk mutant mice. [PDF]
McPeek MK +6 more
europepmc +1 more source
ABSTRACT Objective To estimate miscarriage risk following gestational antimicrobial exposure while addressing biases that have affected previous studies. Design Population‐based cohort study. Setting Linkage of four nationwide registries: Medical Birth Registry of Norway (MBRN), Norwegian Prescribed Drug Registry (NorPD), Norwegian Patient Registry ...
Thomas Boissiere‐O'Neill +3 more
wiley +1 more source
Unraveling the full impact of SPD_0739: a key effector in S. pneumoniae iron homeostasis. [PDF]
Womack E, Antone M, Eichenbaum Z.
europepmc +1 more source
Host Phylogeny and Feeding Habit Jointly Govern Mammalian Gut Microbiota Composition
Herbivores showed higher alpha diversity than carnivores/omnivores, while omnivores had the highest beta diversity. Host phylogeny influenced gut microbiota more strongly in herbivores/omnivores, with phylogenetic distance correlating to microbiota dissimilarity.
Chaoyuan Cheng +3 more
wiley +1 more source
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter +20 more
wiley +1 more source
X-ray diffraction images for two membrane protein crystals presenting high anisotropy; the <i>B. subtilis</i> ABC transporter BmrA and the <i>S. pneumoniae</i> NADPH oxidase. [PDF]
Zampieri V +6 more
europepmc +1 more source
ABSTRACT Introduction Understanding the microbial changes within the surgical site may enhance our understanding of the origin and subsequent role of microbes in the causation of incisional surgical site infections (SSIs). In this study we used 16S rRNA sequencing to establish the dynamic microbiota of the surgical site in patients undergoing bowel ...
Veral Vishnoi +9 more
wiley +1 more source
Comparative Efficacy of Parenteral and Mucosal Recombinant Probiotic Vaccines Against SARS-CoV-2 and S. pneumoniae Infections in Animal Models. [PDF]
Leontieva G +9 more
europepmc +1 more source
Infection control in the brain and the eye
Abstract The Central Nervous System (CNS), comprising the brain and the eye, is considered to have a ‘privileged’ mechanism for dealing with immunological challenge (immune privilege, IP). CNS IP has been revealed through experiments using foreign protein antigens and cell and tissue alloantigens (grafts), but evidence for a role for IP in modulating ...
John V. Forrester +2 more
wiley +1 more source
Blocking HXA3-mediated neutrophil elastase release during S. pneumoniae lung infection limits pulmonary epithelial barrier disruption and bacteremia. [PDF]
Xu S +9 more
europepmc +1 more source

