Identifying genes associated with invasive disease in S. pneumoniae by applying a machine learning approach to whole genome sequence typing data. [PDF]
Obolski U +7 more
europepmc +1 more source
Antimicrobial Resistance and Infant Mortality in Sri Lanka: A Retrospective Cohort Study
ABSTRACT Objective Sepsis is a major cause of mortality among children, with the highest burden evident in neonates and young infants, particularly, in resource‐constrained healthcare settings. Despite this burden, there are insufficient published data to delineate the epidemiology of neonatal sepsis from many of these settings.
Gayana P. S. Gunaratna +8 more
wiley +1 more source
Increased susceptibility of airway epithelial cells from ataxia-telangiectasia to S. pneumoniae infection due to oxidative damage and impaired innate immunity. [PDF]
Yeo AJ +7 more
europepmc +1 more source
ABSTRACT Aim To evaluate clinical features, management, and outcomes of paediatric bone and joint infection (BJI) in a regional Australian hospital and assess weight‐based oral antibiotic prescribing. Methods We conducted a retrospective study of 171 children aged 0–18 years admitted with septic arthritis and/or osteomyelitis between 2011 and 2021 ...
Niall Johnston +2 more
wiley +1 more source
Proteomic and bioinformatic pipeline to screen the ligands of S. pneumoniae interacting with human brain microvascular endothelial cells. [PDF]
Jiménez-Munguía I +9 more
europepmc +1 more source
ABSTRACT Background Meningoencephalitis causes significant morbidity and mortality in children worldwide. Prompt diagnosis remains challenging, yet advances in molecular diagnostic technology have improved diagnostic performance. This study examined whether the introduction of the BioFire FilmArray meningitis/encephalitis (ME) multiplex panel impacted ...
Louisa Mary Churcher +4 more
wiley +1 more source
ABSTRACT The fluoroquinolone antimicrobial agents, enrofloxacin and marbofloxacin, were approved in the United States for cats in 1990 and 2001, respectively. In 2023, revised breakpoints for testing isolates from dogs were published. These canine breakpoints are discordant with the current feline breakpoints.
Mark G. Papich +2 more
wiley +1 more source
A case report of septic shock syndrome caused by S. pneumoniae in an immunocompromised patient despite of vaccination. [PDF]
Singer J +10 more
europepmc +1 more source
Comparison of five genotypic techniques for identification of optochin-resistant pneumococcus-like isolates [PDF]
Claeys, Geert +7 more
core
Impact of Dental Status on Heart Transplantation Outcomes
ABSTRACT Objective Oral infections and poor dental health may contribute to systemic complications after heart transplantation, yet data on their impact is limited. In the absence of standardized dental guidelines for transplant candidates, this study evaluated preoperative dental status and its association with post‐transplant outcomes.
Katharina Theresa Obermeier +8 more
wiley +1 more source

