Heteromeric cis‐prenyltransferases (CPT) are indispensable for dolichol synthesis and protein N‐glycosylation in most eukaryotes. The catalytic subunits are strongly conserved throughout evolution, in contrast to the evolutionarily variable accessory subunits. The POC1 protein from Paramecium tetraurelia is the smallest identified CPT‐accessory subunit
Agnieszka Onysk +8 more
wiley +1 more source
Peptidoglycan Recognition Protein 4 Limits Bacterial Clearance and Inflammation in Lungs by Control of the Gut Microbiota [PDF]
Aly, Sahar +15 more
core +1 more source
Lung organoids as a human system for Mycobacteria infection modeling and drug testing
Mycobacterial infections, including tuberculosis (TB) and infections by nontuberculous mycobacteria (NTM), are still public health issues. In 2023, TB caused 1.25 million deaths, while NTM remain a clinical challenge for patients with cystic fibrosis (CF).
Stephen Adonai Leon‐Icaza +4 more
wiley +1 more source
Mucosal vaccine based on attenuated influenza virus and the group B Streptococcus recombinant peptides protected mice from influenza and S. pneumoniae infections. [PDF]
Desheva Y +7 more
europepmc +1 more source
Pneumolysin Induces 12-Lipoxygenase-Dependent Neutrophil Migration during Streptococcus pneumoniae Infection. [PDF]
Adams W +8 more
europepmc +1 more source
Tissue Resident Memory Cells: Friend or Foe?
Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude +2 more
wiley +1 more source
The Role of Dendritic Cells in S. pneumoniae Transport to Follicular Dendritic Cells. [PDF]
Heesters BA, Carroll MC.
europepmc +1 more source
Evaluation of drug-resistant S treptococcus pneumoniae in patients treated in Pediatric Hospital of Warsaw Medical University in 2012-2013 [PDF]
Małgorzata Dębska +2 more
openalex
ABSTRACT Introduction Pneumonia is a leading cause of death for people with intellectual and developmental disabilities (IDD), who also have increased risk of oral disease. Given the known relationship between oral disease and pneumonia in similar populations, this review aims to explore what is known about the association between oral health and ...
Katrina Byrne +7 more
wiley +1 more source
Abstract Purpose To characterize the microbiota of implant‐supported full‐mandible dentures and its correlation to clinical outcomes for up to 5 years after implant loading in patients with a history of periodontal disease. Materials and Methods Twelve individuals with a history of periodontitis (Stage IV and Grade B) received five immediate implants ...
Jefferson Antônio Gomes +4 more
wiley +1 more source

