Results 261 to 270 of about 20,287,569 (319)

Evolutionary divergence and functional insights into the heteromeric cis‐prenyltransferase of Paramecium tetraurelia

open access: yesThe FEBS Journal, EarlyView.
Heteromeric cis‐prenyltransferases (CPT) are indispensable for dolichol synthesis and protein N‐glycosylation in most eukaryotes. The catalytic subunits are strongly conserved throughout evolution, in contrast to the evolutionarily variable accessory subunits. The POC1 protein from Paramecium tetraurelia is the smallest identified CPT‐accessory subunit
Agnieszka Onysk   +8 more
wiley   +1 more source

Peptidoglycan Recognition Protein 4 Limits Bacterial Clearance and Inflammation in Lungs by Control of the Gut Microbiota [PDF]

open access: yes, 2019
Aly, Sahar   +15 more
core   +1 more source

Lung organoids as a human system for Mycobacteria infection modeling and drug testing

open access: yesThe FEBS Journal, EarlyView.
Mycobacterial infections, including tuberculosis (TB) and infections by nontuberculous mycobacteria (NTM), are still public health issues. In 2023, TB caused 1.25 million deaths, while NTM remain a clinical challenge for patients with cystic fibrosis (CF).
Stephen Adonai Leon‐Icaza   +4 more
wiley   +1 more source

Pneumolysin Induces 12-Lipoxygenase-Dependent Neutrophil Migration during Streptococcus pneumoniae Infection. [PDF]

open access: yesJ Immunol, 2020
Adams W   +8 more
europepmc   +1 more source

Tissue Resident Memory Cells: Friend or Foe?

open access: yesImmunology, EarlyView.
Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude   +2 more
wiley   +1 more source

Oral Health and Pneumonia in Adults With Intellectual and Developmental Disabilities: A Scoping Review

open access: yesJournal of Intellectual Disability Research, EarlyView.
ABSTRACT Introduction Pneumonia is a leading cause of death for people with intellectual and developmental disabilities (IDD), who also have increased risk of oral disease. Given the known relationship between oral disease and pneumonia in similar populations, this review aims to explore what is known about the association between oral health and ...
Katrina Byrne   +7 more
wiley   +1 more source

Microbiota and clinical outcomes of implant‐supported full‐mandible dentures on patients with a history of periodontitis: A 5‐year prospective cohort study

open access: yesJournal of Prosthodontics, EarlyView.
Abstract Purpose To characterize the microbiota of implant‐supported full‐mandible dentures and its correlation to clinical outcomes for up to 5 years after implant loading in patients with a history of periodontal disease. Materials and Methods Twelve individuals with a history of periodontitis (Stage IV and Grade B) received five immediate implants ...
Jefferson Antônio Gomes   +4 more
wiley   +1 more source

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