Results 51 to 60 of about 22,716,326 (258)

A shared mucosal gut microbiota signature in primary sclerosing cholangitis before and after liver transplantation

Hepatology, EarlyView., 2022
In this study of the gut mucosal microbiota in primary sclerosing cholangitis (PSC), we found consistent microbiota features associated with PSC and recurrent PSC, PSC with inflammatory bowel disease and a persistent gut dysbiosis after liver transplantation Abstract Background and Aims Several characteristic features of the fecal microbiota have been ...
Mikal Jacob Hole, Kristin Kaasen Jørgensen, Kristian Holm, Peder R. Braadland, Malin Holm Meyer‐Myklestad, Asle Wilhelm Medhus, Dag Henrik Reikvam, Alexandra Götz, Krzysztof Grzyb, Kirsten Muri Boberg, Tom Hemming Karlsen, Martin Kummen, Johannes R. Hov   +12 more
wiley   +1 more source

The role of the Streptococcus pneumoniae capsule in interactions with complement and phagocytes [PDF]

, 2010
The Streptococcus pneumoniae capsule is an essential virulence factor and it is ideally situated to modulate interactions between the bacteria and host immune cells.
Hyams, C.J.
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A longitudinal household study of Streptococcus pneumoniae nasopharyngeal carriage in a UK setting. [PDF]

, 2005
A 10-month longitudinal household study of pre-school children and their families was undertaken with monthly visits collecting epidemiological data and nasopharyngeal swabs in Hertfordshire, England from 2001 to 2002.
Martin, SA, Edmunds, WJ, Hussain, M, George, R, Efstratiou, A, Miller, E, Pebody, RG, Melegaro, A, Talukdar, R   +8 more
core   +1 more source

Achieving High Spatial Resolution Transmission Electron Microscopy Studies in Closed Liquid Cells

Advanced Materials, EarlyView.
Achieving high spatial resolution is important for resolving nanoscale dynamic processes and structural transformations in liquid environments, yet remains challenging in liquid cell transmission electron microscopy (LCTEM). This review highlights key strategies, including mitigating membrane bulging, displacing or redistributing local liquid ...
Siqi Guo, Hongyu Sun, Le Shu, Xuejin Ge, Raquel Aymerich‐Armengol, Siyuan Zhang, Long Ren, Ningyan Cheng, Christina Scheu, Binghui Ge   +9 more
wiley   +1 more source

Antibiotic Resistance of Streptococcus pneumoniae in the Nasopharynx of Healthy Children Less than Five Years Old after the Generalization of Pneumococcal Vaccination in Marrakesh, Morocco

Antibiotics, 2023
Streptococcus pneumoniae (S. pneumoniae) remains one of the most important pathogens causing childhood infections. The spread of antibiotic-resistant bacteria is a leading cause of treatment failure in children.
Sara Amari, Karima Warda, Majda Bouraddane, Mostafa Katfy, Youssef Elkamouni, Lamiae Arsalane, Khalid Zerouali, Said Zouhair, Mohamed Bouskraoui   +8 more
doaj   +1 more source

Fecal shedding of Klebsiella pneumoniae by dairy cows [PDF]

, 2006
Klebsiella pneumoniae is a common cause of clinical mastitis in dairy cattle. Wood products are considered to be the main source of Klebsiella on dairy farms.
Rauch, B.J., Zadoks, R. N., Munoz, M. A., Ahlström, C., Zadoks, R.N., Munoz, M.A., Rauch, B. J., M.A. Munoz, B.J. Rauch, R.N. Zadoks, C. Ahlström   +10 more
core   +1 more source

The Natural Product Corramycin Acts as a DNA Gyrase Poison and Overcomes Fluoroquinolone Resistance in Mycobacterium tuberculosis

Advanced Science, EarlyView.
Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries, Jennifer Herrmann, Michael Dal Molin, Yaëlle Wormser, Timo Risch, Yunsheng Gao, Gareth Prosser, Francesca Gubellini, Ariel Mechaly, Joshua B. Wallach, Anthony Castro, Arka Banerjee, Sari Rasheed, Alexander Horn, Mathias Müsken, Michael Kurz, Lindsay Sonnenkalb, Viola Dreyer, Stefan Niemann, Sönke Andres, Dirk Schnappinger, Uli Kazmaier, Norbert Reiling, Rolf Müller, Jan Rybniker, Stéphanie Petrella   +25 more
wiley   +1 more source

Structure and Biosynthesis of Mangotoxin Produced by the Plant Pathogen Pseudomonas syringae

Angewandte Chemie, EarlyView.
The structure of mangotoxin remained elusive for over two decades. Here, mangotoxin was isolated from the native producer, Pseudomonas syringae pv. syringae, and was determined to be an alkyne‐containing dipeptide. Mangotoxin inhibited the growth of multidrug‐resistant human pathogen Klebsiella pneumoniae.
Alexis H. Murray, Sohan Hazra, Ryan W. Mull, Erinn M. O'Neill, Bo Li   +4 more
wiley   +2 more sources

The Influence of B Cell Depletion Therapy on Naturally Acquired Immunity to Streptococcus pneumoniae

Frontiers in Immunology, 2021
The anti-CD20 antibody Rituximab to deplete CD20+ B cells is an effective treatment for rheumatoid arthritis and B cell malignancies, but is associated with an increased incidence of respiratory infections.
Giuseppe Ercoli, Elisa Ramos-Sevillano, Rie Nakajima, Rafael Ramiro de Assis, Algis Jasinskas, David Goldblatt, Philip Felgner, Gisbert Weckbecker, Jeremy Brown   +8 more
doaj   +1 more source

Antibody responses to nasopharyngeal carriage of Streptococcus pneumoniae in adults: A longitudinal household study [PDF]

, 2005
Background. Natural immunity to Streptococcus pneumoniae is thought to be induced by exposure to S. pneumoniae or cross-reactive antigens. No longitudinal studies of carriage of and immune responses to S.
Hussain, M, Virta, C, Soininen, A, Kayhty, H, Miller, E, Ashton, L, Edmunds, J, Gay, N, Goldblatt, D, Andrews, N, George, R, Pebody, R, Melegaro, A   +12 more
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