Results 41 to 50 of about 6,450 (126)

Immune Checkpoint Inhibitors and Immunomodulators for Cancer Immunotherapy: Insights Into Resistance and Therapeutic Strategies

open access: yesAdvanced Science, Volume 13, Issue 25, 4 May 2026.
The schematic diagram illustrates the roles of novel immune checkpoints, immunomodulatory factors, cell death and multimodal technologies in cancer immunotherapy. Abstract Cancer immunotherapy has redefined cancer treatment. However, the molecular and cellular basis of immune evasion and therapeutic resistance remains incompletely understood.
Fangquan Chen   +7 more
wiley   +1 more source

CA2 Pyramidal Layer

open access: yes, 2008
This report contains a gene expression summary of the CA2 pyramidal cell layer (CA2sp), derived from the Allen Brain Atlas (ABA) in situ hybridization mouse data set.
Rachel A. Dalley   +6 more
core   +1 more source

Glucose metabolic reprogramming as a driver of immunosuppression in the tumour microenvironment

open access: yesClinical and Translational Medicine, Volume 16, Issue 5, May 2026.
Glucose metabolic reprogramming is a central driver of immunosuppression in the tumour microenvironment, orchestrating immune dysfunction through multiple interconnected mechanisms. Glucose competition establishes a selective bioenergetic hierarchy that constrains antitumour immunity, whereas lactate accumulation and its reciprocal crosstalk with ...
Yang Wang   +3 more
wiley   +1 more source

Brain–specific proteins in Multiple Sclerosis

open access: yes, 2003
Brain–specific proteins (BSP) are each relatively specific for particular cell–types within the nervous system. The BSP studied were glial fibrillary acidic protein (GFAP) and S100B for the astrocyte, ferritin for microglia and neurofilaments (Nf) for ...
Petzold, A.
core  

A Meta-Analysis: Significance of Biofluid Biomarkers in Sports-Related Traumatic Brain Injury

open access: yes, 2022
Background: To reduce the reliance on clinical judgment for the regulation of sports-related traumatic brain injury, identifying and measuring objective to biofluid biomarkers can provide important insight into the diagnosis (Determining the type and ...
Oliveira, Stephanie
core  

Self-inactivating gammaretroviral vectors for the gene therapy of chronic granulomatous disease

open access: yes, 2008
Chronic granulomatous disease (CGD) is a rare inherited primary immunodeficiency characterized by defective intracellular oxidative killing of ingested invading microbes by PMN and monocytes.
Moreno Carranza, Bibiana
core  

Role of the immune system during the development of acute and chronic renal disease [PDF]

open access: yes, 2013
PhD ThesisThe purpose of this thesis was to investigate the contribution of the inflammatory mediators Nuclear factor κB and complement during the progression of renal diseases.
Fearn, Amy
core  

Untersuchungen auf zellulärer Ebene zur Entstehung von Endometritis in Kühen

open access: yes, 2018
Nearly half of dairy cows develop uterine diseases in the first weeks after parturition, the most common manifestation being endometritis. Such diseases profoundly affect reproductive performance and reduce the profit potential of dairy farms, with an ...
Ibrahim, Mohammad Abdelwahab Ali
core   +1 more source

Диагностическая значимость белка S100B при критических состояниях

open access: yes, 2011
The review deals with possibilities for the quantitative assessment of the degree of brain injury, by measuring the level of S100B protein in various biological fluids.
N. V. Beloborodova   +5 more
core   +1 more source

Morphological plasticity of astroglia: Understanding synaptic microenvironment

open access: yes, 2015
Memory formation in the brain is thought to rely on the remodeling of synaptic connections which eventually results in neural network rewiring. This remodeling is likely to involve ultrathin astroglial protrusions which often occur in the immediate ...
Rusakov, DA, Heller, JP
core  

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