Results 21 to 30 of about 6,450 (126)

Harnessing blood clot as a native scaffold for orchestrating tissue repairs and regeneration

open access: yesBMEMat, EarlyView.
The blood clot, owing to its dynamic composition and unique microenvironment, holds significant yet underappreciated potential for tissue engineering. This review systematically summarizes the pathophysiology of clot formation, the key regulatory factors shaping its microenvironment, and its applications in both pre‐clinical and clinical settings ...
Gao‐peng Dang   +13 more
wiley   +1 more source

Exercise‐specific plasma proteomic signatures in racehorses: Candidates for training adaptation and peak load monitoring

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Racehorses undergo profound physiological changes with training and competition, but current biomarkers inadequately capture the complex molecular dynamics of exercise. This study aimed to identify novel plasma biomarkers of training adaptation and peak load using high‐throughput proteomics.
Jowita Grzędzicka   +4 more
wiley   +1 more source

Primary and secondary antibodies used for immunohistochemistry.

open access: yes, 2012
Aldh1, aldehyde dehydrogenase–1; APC adenomatous polyposis coli; CD11b, integrin alpha M; DCX, doublecortin; GFAP, glial fibrillary acidic protein; GFP, green fluorescent protein; GLAST, glutamate/aspartate transporter; NG2, chondroitin sulfate ...
Helena Pivonkova (165631)   +4 more
core   +1 more source

Recent progress on the development of hydrogel‐based microneedles for transdermal drug delivery

open access: yesVIEW, EarlyView.
This study provides a comprehensive and up‐to‐date analysis of recent progress in HMN technology, covering fundamental transdermal delivery mechanisms and design principles, biomaterials used in HMN fabrication, drug loading and release strategies, and emerging therapeutic applications.
Mohammad Muhtasim Ittisaf   +5 more
wiley   +1 more source

Proteomics of chronic pressure ulcers

open access: yes, 2012
Analysis of the proteomic profile of pressure ulcers over time is a critical step in the identification of biomarkers of healing or nonhealing in pressure ulcers.
Edsberg, Laura E.   +7 more
core   +1 more source

Proteolytic remodelling of the extracellular matrix by pericytes

open access: yesThe FEBS Journal, EarlyView.
Pericytes are specialised perivascular cells intimately connected with endothelial cells and essential for the maintenance of vascular beds. They contribute to the formation and remodelling of the extracellular matrix by actively secreting proteases and protease inhibitors.
Tina Burkhard   +4 more
wiley   +1 more source

Neutrophil Secretory Proteins Inhibit Calcium Oxalate Crystallisation and Crystal Growth, but Promote Crystal Aggregation

open access: yesImmunology, EarlyView.
Calcium oxalate monohydrate (COM) crystals cause changes in the secretion of 29 proteins from neutrophil‐like cells, including those involved in neutrophil immune activation and intracellular metabolic adaptation. The neutrophil secreted proteins (secretome) also inhibit calcium oxalate crystallisation and crystal growth, but promote crystal ...
Chanettee Lertprapai   +2 more
wiley   +1 more source

Estudo dos derivados da guanina como agentes protetores e tróficos em astrócitos e neurônios cerebelares [PDF]

open access: yes, 2004
Dissertação (mestrado) - Universidade Federal de Santa Catarina. Centro de Ciências Biológicas. Programa de Pós-Graduação em Neurociências.Os nucleotídeos e o nucleosídeo derivados da guanina (DG) têm sido implicados em diversas funções extracelulares ...
Francisco, Sheila Regina Schmidt
core  

Autophagy-based unconventional secretion of HMGB1 by keratinocytes plays a pivotal role in psoriatic skin inflammation

open access: yes, 2020
The precise mechanism through which macroautophagy/autophagy affects psoriasis is poorly understood. Here, we found that keratinocyte (KC) autophagy, which was positively correlated with psoriatic severity in patients and mouse models and could be ...
Zhen Wang (72451)   +27 more
core   +1 more source

The MacBrain Resource Center (MBRC) rhesus macaque postnatal brain histology datasets: Enabling new discoveries through NHP tissue and digital data Repositories

open access: yesJournal of Anatomy, EarlyView.
The MacBrain Resource Center (MBRC) postnatal rhesus macaque brain histology datasets are organized into Collections that promote cost‐effective de novo research. This article provides examples from Collections 5, 6, and 7 and describes the histo‐ and immunohistochemical (IHC) processing of materials for Collection 6.
Valeria Mendoza‐Silva   +19 more
wiley   +1 more source

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