Results 11 to 20 of about 6,450 (126)
Hepatology, EarlyView., 2022 Mesenchymal stem cells subset, educated by TNF‐α, are involved to generate inflammatory microenvironment and promote hepatocarcinogenesis Abstract Background and Aims Increasing evidence suggests that mesenchymal stem cells (MSCs) home to injured local tissues and the tumor microenvironment in the liver.
Chen Zong +9 more
wiley +1 more source
Hepatology, EarlyView., 2022 CHIN117 is a dual cysteinyl leukotriene receptor 1 (CYSLTR1) antagonist and G‐protein‐coupled bile acid receptor 1 (GPBAR1) agonist. In the liver, GPBAR1 and CYSLTR1 are coexpressed by liver sinusoidal endothelial cells (LSECs), HSCs, circulating monocytes/macrophages, and liver resident macrophages (Kupffer cells).
Michele Biagioli +13 more
wiley +1 more source
Hepatology, EarlyView., 2022 Lrat+ quiescent hepatic stellate cells (qHSC) give rise to Lrat+Fbln2+ activated HSC (aHSC) in alcohol‐associated hepatitis and this subpopulation is highly profibrotic, inflammatory, and immunoregulatory based on their single cell transcriptomic profile. Abstract Background and Aims Relative roles of HSCs and portal fibroblasts in alcoholic hepatitis (
Steven Balog +12 more
wiley +1 more source
Mechanism of activation of NDR protein kinase by the HMOB1 protein [PDF]
, 2005 Serine/threonine kinases of the nuclear Dbf2-related (NDR) family are highly conserved throughout the eukaryotic world. Members of this kinase family are implicated in various aspects of the regulation of cell division and cell morphology. It has been
Bichsel, Samuel J.
core +1 more source
Dysregulated genes in podocytes in different FSGS models.
, 2020 An overlap of three independent mRNA expression profiles (miR-193, Actn4-/-, Fyn-/-;Cd2ap+/-,) during FSGS reveals nine commonly upregulated genes (red arrow) and one downregulated gene (green arrow).
Eva Nora Bukosza (6524357) +5 more
core +1 more source
Identification of new genes associated with melanoma
, 2011 Purpose: Repeated failures in melanoma therapy made clear that the molecular mechanisms leading to melanoma are still poorly understood. Here, we aim to provide a more comprehensive understanding of the transcriptional profiles and signaling pathways ...
Mauerer, Andreas
core +1 more source
Metabolic syndrome influences cardiac gene expression pattern at the transcript level in male ZDF rats [PDF]
, 2013 Background: Metabolic syndrome (coexisting visceral obesity, dyslipidemia, hyperglycemia, and hypertension) is a prominent risk factor for cardiovascular morbidity and mortality, however, its effect on cardiac gene expression pattern is unclear ...
Ágnes Zvara +37 more
core +1 more source
Functional association network analysis of 2D MS identified proteins.
, 2012 A. Protein–protein interactions among the 30 identified proteins were analyzed using STRING 8.0. Twelve of the proteins were functionally associated with the major cytoskeletal network. B.
Jin Han (9149) +14 more
core +1 more source
Animal Research and One Health, EarlyView.Basic research on the PEDV infection cycle and virus–host interactions advances the development of anti‐PEDV drugs and disease‐resistant breeding and helps strengthen disease prevention and control while reducing economic losses in the swine industry.
Heyong Wu +8 more
wiley +1 more source
Functions and pathways of differential proteins. (Enrichment p-value<0.05).
, 2013 Protein names corresponded to gene symbols: S100A6:S100 calcium binding protein A6; DTYMK:deoxythymidylatekinase; PA2G4:proliferation-associated 2G4; STAG2:stromal antigen 2; PCNA:proliferating cell nuclear antigen; PRKRA: interferon-inducible double ...
Yong Han (111920) +7 more
core +1 more source