Results 161 to 170 of about 15,017 (189)

BRD4L cooperates with MYC to block local tumor invasion via suppression of S100A10.

Cellular Signalling
Targeted therapy based on BRD4 and MYC shows promise due to their well-researched oncogenic functions in cancer, but their tumor-suppressive roles are less understood.
Yong Ma, N. Liu, Yushu Shi, Shuyan Ma, Yingjun Wang, Wen Zheng, Rong Sun, Yihua Song, Miaomiao Chen, Lishuai Qu, Renfang Mao, Yihui Fan   +11 more
semanticscholar   +1 more source

Roles of S100A1 and S100A10 from hybrid grouper (Epinephelus lanceolatus♂ × Epinephelus fuscoguttatus♀) in the immune response to Vibrio infection.

Fish and Shellfish Immunology
The S100 proteins are highly conserved EF-hand calcium-binding proteins found only in vertebrates. In the current study, two S100 genes (S100A1 and S100A10) were successfully identified and characterized from hybrid grouper Epinephelus lanceolatus ...
Sheng Yuan, Ying Huang, Quan Wang, Yan-Ru Shi, Xiaorui Song, Zhe Zhao   +5 more
semanticscholar   +1 more source

p11 (S100A10) — an inducible adaptor protein that modulates neuronal functions

Current Opinion in Pharmacology, 2007
p11 (S100A10) is a member of the S100 protein family and forms a heterotetrameric complex with annexin 2. p11 has also been found to interact with a diverse set of proteins that includes several ion channels and the serotonin 5-HT1B receptor. Several factors such as dexamethasone, growth factors, nitric oxide and antidepressant therapies regulate the ...
Per, Svenningsson, Paul, Greengard
openaire   +2 more sources

Annexin A2 orchestrates CSFV entry route selection via the annexin A2/S100A10 heterotetrameric complex.

Veterinary Microbiology
Classical swine fever virus (CSFV) is a highly contagious pathogen that causes substantial economic losses in swine production, yet the mechanisms governing its cellular entry remain poorly defined.
Tao Wang, Liangcai Da, Junfang Zhao, Hong Yuan, Ying Sun, Liang Zhang, Jiaoyang Li, Kun Li, Jing Zhang, P. Sun, Zhixun Zhao, Qiang Zhang, Yuanji Zhang, Yebin Liu, Xingwen Bai, Zengjun Lu   +15 more
semanticscholar   +1 more source

P11 (S100A10) as a potential biomarker of psychiatric patients at risk of suicide

Journal of Psychiatric Research, 2011
Although suicide represents 1.8% of the global burden of disease, there are few objective assays for suicide risk. Being associated with depressive disorders, which have a high risk of suicide, the proteins P11, P2RX7, and S100β may be biomarkers for a suicidal disposition. We measured levels of p11 and P2RX7 mRNA in peripheral blood mononuclear cells (
Lei, Zhang, Tung-Ping, Su, Kwang, Choi, Webster, Maree, Cheng-Ta, Li, Ming-Yi, Chung, Ying-Sheue, Chen, Ya-Mei, Bai, Yuan-Hwa, Chou, Jeffery L, Barker, James E, Barrett, Xiao Xia, Li, He, Li, David M, Benedek, Robert, Ursano   +14 more
openaire   +2 more sources

N-terminal acetylation of annexin A2 is required for S100A10 binding

bchm, 2012
Abstract Annexin A2 (AnxA2), a Ca2+-regulated phospholipid binding protein involved in membrane-cytoskeleton contacts and membrane transport, exists in two physical states, as a monomer or in a heterotetrameric complex mediated by S100A10. Formation of the AnxA2-S100A10 complex is of crucial regulatory importance because only the complex
Ali Reza, Nazmi, Gabriel, Ozorowski, Milena, Pejic, Julian P, Whitelegge, Volker, Gerke, Hartmut, Luecke   +5 more
openaire   +2 more sources

Neurogenic Effects of Fluoxetine Are Attenuated in p11 (S100A10) Knockout Mice

Biological Psychiatry, 2010
Chronic but not acute treatment with antidepressants increases hippocampal neurogenesis. Because chronic treatment with antidepressants also upregulates p11, we hypothesized that p11 might regulate effects of antidepressants on aspects of neurogenesis.Fluoxetine was administered chronically to wild-type (WT) and p11 knockout (KO) mice.
Egeland, Martin, Warner-schmidt, Jennifer, Greengard, Paul, Svenningsson, Per   +3 more
openaire   +3 more sources

ASS1 Promotes Colorectal Cancer Immune Evasion Through CPT1A-Mediated S100A10 Succinylation.

Frontiers in Bioscience
BACKGROUND Colorectal cancer (CRC) progression is frequently driven by metabolic reprogramming and immune evasion. A crucial metabolic enzyme, argininosuccinate synthetase 1 (ASS1), is dysregulated in a number of malignancies; however, its role in CRC ...
Liping Sun, Daidi Fu, Heng Zhang
semanticscholar   +1 more source

[The expression and antibody preparation of S100A10 protein].

Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2015
To prepare S100A10 protein and its specific polyclonal antibody.The full-length gene fragment of S100A10 was amplified by PCR, and then cloned into pET28a(+) prokaryotic expression vector. After transformation, the vector was induced to express the recombinant (S100A10)(2) protein by IPTG in E.coli BL21 (DE3).
Dandan, Xin, Xiaohua, Zou, Manzhen, Zuo, Chaoqi, Liu   +3 more
openaire   +1 more source

The Calcium‐Binding Protein S100A10 (p11) Is Required for Normal Motor Performance by Regulating Vesicle Dynamics at Excitatory Synapses

Acta Physiologica
Identifying interactors in sensorimotor processing and neurotransmission remains a current challenge for understanding neural information processing and brain function.
Esther Vilches-Herrando, Guillermo Rodríguez-Bey, Rosendo G. Hernández, Ángela Gento-Caro, A. Pastor, A. Campos-Caro, David González-Forero, B. Moreno-López   +7 more
semanticscholar   +1 more source