Results 141 to 150 of about 217,790 (251)

Deep Learning Enables Identification of Antimicrobial Peptides Through Mechanochromic Fingerprints

Angewandte Chemie, EarlyView.
We demonstrate a new platform for antimicrobial peptide identification by combining polydiacetylene, hyperspectral imaging, and deep learning. The trained model classifies distinct spectral fingerprints into 14 peptide classes with 96.79% accuracy, revealing previously hidden molecular information beyond conventional colorimetric sensing.
Jiali Chen, Che‐Lun Chin, Qingzhen Zhu, Ling Chao, Kaori Sugihara   +4 more
wiley   +2 more sources

Diverse Bacterial Properties Influence Dispersal Along Fungal Networks. [PDF]

J Fungi (Basel)
Regalado R, Silva MSC, Price E, Liang NW, Grunenwald CM, Sauer JD, Beebe DJ, Keller NP.   +7 more
europepmc   +1 more source

Modified Titanium Dental Implants: The Current Progress of Soft‐Tissue Integration Methods

Advanced NanoBiomed Research, EarlyView.
Dental implants are an established solution for tooth loss, yet achieving soft tissue integration (STI) around the transmucosal region remains a challenge. The natural tooth–gingiva interface is poorly replicated on titanium implants. This review explores surface modification strategies, ranging from surface chemistry and topography to biological ...
Daniel De Maria, Amy Gelmi, Peter C. Sherrell, Stefan Di Medio, Nhiem Tran, Kate Fox   +5 more
wiley   +1 more source

Chemoenzymatic Radiosynthesis of a Gluconate Transporter‐Targeted In Vivo Bacterial Sensor From Clinical [18F]FDG

Angewandte Chemie, EarlyView.
An efficient radiosynthesis of fluorine‐18 labeled gluconic acid ([18F]FGA) was developed using two readily available materials, 2‐deoxy‐2‐[18F]fluoro‐D‐glucose ([18F]FDG) and glucose oxidase. [18F]FGA is highly specific for bacterial gluconate metabolism mediated by gluconate permease (GntP) and gluconate kinase (GntK), with rapid clearance, low off ...
Sang Hee Lee, Jung Min Kim, Joseph Blecha, Robert R. Flavell, Michael A. Ohliger, Joanne Engel, Youngho Seo, David M. Wilson   +7 more
wiley   +2 more sources

The effect of elevated physiological temperatures on bacterial survival and antibiotic susceptibility in an <i>in vitro</i> infection prevention model. [PDF]

Front Microbiol
Kamphof R, Verheul M, Nelissen RGHH, de Boer MGJ, Pijls BGCW.   +4 more
europepmc   +1 more source

Nanostructured Deep Eutectic Systems in Healthcare: From Bioactive Solvents to Intelligent Biointerfaces, Wearables, and AI‐Driven Design

Advanced NanoBiomed Research, EarlyView.
Beyond the green solvent paradigm, this review redefines Deep Eutectic Systems (DES) as programmable supramolecular nanoassemblies. We survey their biomedical convergence: stabilizing thermolabile mRNA to enable cold chain‐free logistics, reshaping transdermal microneedle delivery, enabling long‐term wearables via eutectogels, and utilizing Generative ...
Jeesu Moon, Min Seo Kim, Jae‐Seung Lee
wiley   +1 more source

Repression of Virulence in Staphylococcus aureus by 2‐Aminothiol‐Mediated Quorum Quenching

Angewandte Chemie, EarlyView.
Simple analogues of cysteine that can eliminate the native autoinducing peptides (AIPs) of staphylococci extracellularly, before they activate their receptor, and turn off quorum sensing in different Staphylococcus aureus. The elimination of AIPs occurs through a mechanism similar to native chemical ligation (NCL). Further, this strategy showed promise
Bengt H. Gless, Riccardo Milazzo, Martin S. Bojer, Benjamin S. Sereika‐Bejder, Hanne Ingmer, Christian A. Olsen   +5 more
wiley   +2 more sources

Prevalence and Antimicrobial Susceptibility Patterns of Nosocomial Bacteria across Different Units at King Faisal Complex Hospital, Taif, Kingdom of Saudi Arabia. [PDF]

Saudi Med J
Hawsawi N, Al-Jaiud RN, Khyyat LL, Alsulimany K, Shabat M.   +4 more
europepmc   +1 more source

Green Synthesis of Magnesium Nitrate Nanoparticles Using <i>Momordica charantia</i> Peel Extract: Enhanced Antibacterial Activity and Antibiotic Potentiation Against Multidrug-Resistant Bacteria with Low Acute Toxicity. [PDF]

Nanomaterials (Basel)
Naz I, Niaz H, Rehman A, Hussain M, Abdelmalek IB, Shuja MN, Anees M.   +6 more
europepmc   +1 more source

Reciprocal adaptation is critical in enhancing S. aureus and P. aeruginosa biofilm biomass. [PDF]

Arch Microbiol
Sun X, Cooksley CM, Awad M, Barry EF, Psaltis AJ, Wormald PJ, Vreugde S.   +6 more
europepmc   +1 more source