Results 131 to 140 of about 26,823 (310)
Precision therapies for genetic epilepsies in 2025: Promises and pitfalls
Epilepsia Open, EarlyView.Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang +3 more
wiley +1 more source
The effect of word frequency and parafoveal preview on saccade length during the reading of Chinese
, 2016 There are currently 2 theoretical accounts of how readers of Chinese select their saccade targets: (a) by moving their eyes to specific saccade targets (i.e., the default-targeting hypothesis) and (b) by adjusting their saccade lengths to accommodate ...
Reichle, Erik D. +3 more
core +1 more source
Absence seizures: Update on signaling mechanisms and networks
Epilepsia Open, EarlyView.Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley +1 more source
Anti-saccades predict cognitive functions in older adults and patients with Parkinson's disease.
PLoS ONE, 2018 A major component of cognitive control is the ability to act flexibly in the environment by either behaving automatically or inhibiting an automatic behaviour.
Julie Ouerfelli-Ethier +5 more
doaj +1 more source
, 2015 This study investigated the effect of hand movements on behavioral and electrophysiological parameters of saccade preparation. While event-related potentials were recorded in 17 subjects, they performed saccades to a visual target either together with a ...
Sailer, Uta, +5 more
core +1 more source
Epilepsia Open, EarlyView.Abstract Objective Individuals with Down syndrome (DS) face an ultra‐high risk of Alzheimer's disease (AD). Within this continuum, Progressive Myoclonus Epilepsy (PME) has emerged as a marker of advanced neurodegeneration. Building on our 2014 characterization of this syndrome, we aimed to define its long‐term natural history and pathological substrate.
Giuseppe d'Orsi +6 more
wiley +1 more source
Epilepsia Open, EarlyView.The impact of prompt diagnosis and treatment, and early predictors of outcome severity in this cohort. Abstract Objective Most therapies for drug‐resistant epilepsy (DRE) focus on focal‐onset seizures, the most common seizure types. Studying primary generalized tonic–clonic seizures (PGTCS) is more challenging due to diagnostic and recruitment ...
Katherine Eggleston +6 more
wiley +1 more source
Presaccadic attentional shifts are not modulated by saccade amplitude
Scientific ReportsHumans constantly explore the visual environment through saccades, bringing relevant visual stimuli to the center of the gaze. Before the eyes begin to move, visual attention is directed to the intended saccade target.
Luan Zimmermann Bortoluzzi +4 more
doaj +1 more source