Results 31 to 40 of about 18,399 (262)

Adaptation of saccadic sequences with and without remapping

Frontiers in Human Neuroscience, 2016
It is relatively easy to adapt visually-guided saccades because the visual vector and the saccade vector match. The retinal error at the saccade landing position is compared to the prediction error, based on target location and efference copy.
Delphine Lévy-Bencheton, Aarlenne Zein Khan, Denis Pélisson, Caroline Tilikete, Laure Pisella   +4 more
doaj   +1 more source

GIVE me your attention: Differentiating goal identification and goal execution components of the anti-saccade effect.

PLoS ONE, 2019
The anti-saccade task is a commonly used method of assessing individual differences in cognitive control. It has been shown that a number of clinical disorders are characterised by increased anti-saccade cost.
Owen Myles, Ben Grafton, Patrick Clarke, Colin MacLeod   +3 more
doaj   +1 more source

Oculomotor adaptation elicited by intra-saccadic visual stimulation: time-course of efficient visual target perturbation.

Frontiers in Human Neuroscience, 2016
Perception of our visual environment strongly depends on saccadic eye movements, which in turn are calibrated by saccadic adaptation mechanisms elicited by systematic movement errors. Current models of saccadic adaptation assume that visual error signals
Muriel ePanouilleres, Muriel ePanouilleres, Valerie eGaveau, Jeremy eDebatisse, Patricia eJacquin, Marie eLeBlond, Denis ePélisson   +6 more
doaj   +1 more source

Identifying an oculomotor phenotype for adolescent depression with an interleaved pro- and anti-saccade task

Frontiers in Psychiatry
IntroductionNumerous studies have shown that adults with depression have distinct oculomotor alterations during saccade tasks, but whether similar alterations occur in adolescents is largely unknown.
Blake K. Noyes, Linda Booij, Linda Booij, Heidi C. Riek, Brian C. Coe, Don C. Brien, Sarosh Khalid-Khan, Sarosh Khalid-Khan, Douglas P. Munoz, Douglas P. Munoz   +9 more
doaj   +1 more source

Saccadic Eye Movements are Related to Turning Performance in Parkinson Disease

Journal of Parkinson’s Disease, 2011
Background. Persons with Parkinson disease (PD) experience difficulty turning, leading to freezing of gait and falls. We hypothesized that saccade dysfunction may relate to turning impairments, as turns are normally initiated with a saccade.
Corey A. Lohnes, Gammon M. Earhart
doaj   +1 more source

Voluntary saccade inhibition deficits correlate with extended white-matter cortico-basal atrophy in Huntington's disease

NeuroImage: Clinical, 2017
The ability to inhibit automatic versus voluntary saccade commands in demanding situations can be impaired in neurodegenerative diseases such as Huntington's disease (HD).
Israel Vaca-Palomares, Brian C. Coe, Donald C. Brien, Aurelio Campos-Romo, Douglas P. Munoz, Juan Fernandez-Ruiz   +5 more
doaj   +1 more source

Saccadic suppression of displacement in face of saccade adaptation

Vision Research, 2011
Saccades challenge visual perception since they induce large shifts of the image on the retina. Nevertheless, we perceive the outer world as being stable. The saccadic system also can rapidly adapt to changes in the environment (saccadic adaptation). In such case, a dissociation is introduced between a driving visual signal (the original saccade target)
Klingenhoefer, S., Bremmer, F.
openaire   +2 more sources

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source

Cortical Activation during Landmark-Centered vs. Gaze-Centered Memory of Saccade Targets in the Human: An FMRI Study

Frontiers in Systems Neuroscience, 2017
A remembered saccade target could be encoded in egocentric coordinates such as gaze-centered, or relative to some external allocentric landmark that is independent of the target or gaze (landmark-centered).
Ying Chen, Ying Chen, Ying Chen, J. D. Crawford, J. D. Crawford, J. D. Crawford, J. D. Crawford   +6 more
doaj   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source