Results 201 to 210 of about 137,997 (266)

Fibroblasts and hiPS‐Derived Astrocytes From CoPAN Patients Showed Different Levels of Iron Overload Correlated With Senescent Phenotype

open access: yesGlia, Volume 73, Issue 7, Page 1467-1482, July 2025.
Main Points CoPAN affects CoA biosynthesis and leads to iron dyshomeostasis. CoPAN d‐astrocytes show ferroptosis, iron accumulation, senescence, lipid peroxidation, mitochondrial damage and tubulin acetylation loss. Astrocytes recapitulate CoPAN disease.
Anna Cozzi   +8 more
wiley   +1 more source

Ancestral sequence reconstruction of the Mic60 Mitofilin domain reveals residues supporting respiration in yeast

open access: yesProtein Science, Volume 34, Issue 7, July 2025.
Abstract In eukaryotes, cellular respiration takes place in the cristae of mitochondria. The mitochondrial inner membrane protein Mic60, a core component of the mitochondrial contact site and cristae organizing system, is crucial for the organization and stabilization of crista junctions and its associated functions.
Friederike M. C. Benning   +11 more
wiley   +1 more source

Aminoisothiazolamides, a new class of potent inhibitors of lysyl‐tRNA synthetase

open access: yesPest Management Science, Volume 81, Issue 7, Page 3956-3983, July 2025.
The present work covers a series of novel herbicidal lead structures that possess an aminoisothiazolamide scaffold as a structural key feature. Lysyl‐tRNA synthetase 1 (KRS1) was identified as the biochemical mode‐of‐action. Based on optimized and tailored synthetic approaches, a broader SAR study was carried out delivering some lead structures that ...
David Bernier   +26 more
wiley   +1 more source

Computational analysis of polymorphic residues in maltose and maltotriose transporters of a wild <i>Saccharomyces cerevisiae</i> strain. [PDF]

open access: yesOpen Life Sci
Faz-Cortez OA   +5 more
europepmc   +1 more source

Hybridization in Meat‐Based Dual Protein Foods: Mechanisms, Challenges, and Consumer Insights

open access: yesComprehensive Reviews in Food Science and Food Safety, Volume 24, Issue 4, July 2025.
ABSTRACT As the global demand for protein‐rich foods continues to rise, developing innovative solutions to enhance sustainability and nutritional quality in meat production has become increasingly important. Meat is a tasty source of high‐quality protein and micronutrients, whose integration with alternative proteins offers new avenues to address ...
Renyu Zhang   +3 more
wiley   +1 more source

Bioprotection with <i>Saccharomyces cerevisiae</i>: A Promising Strategy. [PDF]

open access: yesMicroorganisms
El Dana F   +5 more
europepmc   +1 more source

Innovations in Edible Packaging Films, Coatings, and Antimicrobial Agents for Applications in Food Industry

open access: yesComprehensive Reviews in Food Science and Food Safety, Volume 24, Issue 4, July 2025.
ABSTRACT Packaging reduction, particularly in terms of single‐use plastic (SUP) packaging waste, as well as restrictions on specific packaging formats and regulatory requirements, are driving the demand for sustainable packaging solutions. Notably, within the category of SUP products, packaging accounts for the highest share at 40%. Therefore, advanced
Lokesh Kumar   +3 more
wiley   +1 more source

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