Results 221 to 230 of about 137,997 (266)

The Direct and Individual Transcriptional Function of the Human Homodimeric and Heterodimeric Basic Helix–Loop–Helix Transcription Factors E47 and Scleraxis

open access: yesThe FASEB Journal, Volume 39, Issue 12, 30 June 2025.
The isolated yeast model allowed visualization of the function of the heterodimeric SCX and E47 transcription factors (TFs) in the absence of other interacting proteins. The findings support the need for additional transcription factor binding sites (TFBS) and a permissive chromatin landscape for these TFs to exert a positive transcriptional effect ...
Karla Miranda López‐Delucio   +5 more
wiley   +1 more source

Characterization of a consensus-designed <i>trans</i>-cinnamic acid decarboxylase for styrene biosynthesis. [PDF]

open access: yesmBio
García-Franco A   +6 more
europepmc   +1 more source

Terpenes and Terpenoids: How can we use them?

open access: yesEuropean Journal of Organic Chemistry, Volume 28, Issue 24, June 24, 2025.
The transition from petroleum‐based to renewable bio‐based chemicals has led to increased interest in terpenes and terpenoids. This overview highlights their chemistry, focusing on their reactivity and applications in polymerizations, total syntheses, pharmaceuticals, and bio‐based chemical conversions; promoting sustainable and green chemical ...
Jay Hanssens   +3 more
wiley   +1 more source

Synthesis of 2‐Substituted Adenosine Triphosphate Derivatives and their use in Enzymatic Synthesis and Postsynthetic Labelling of RNA

open access: yesChemBioChem, Volume 26, Issue 12, June 16, 2025.
A series of 2‐substituted adenosine 5′‐O‐triphosphate derivatives is synthesized and tested as substrates for polymerases. In vitro transcription with T7 RNA polymerase, primer extension with engineered DNA polymerases, or 3′‐labelling with poly(A) polymerase are used for enzymatic synthesis of base‐modified RNA.
Ugnė Šinkevičiūtė   +5 more
wiley   +1 more source

Designing Enzymatic Reactivity with an Expanded Palette

open access: yesChemBioChem, Volume 26, Issue 11, June 3, 2025.
Innovation in biocatalysis is rapidly increasingly the diversity of catalytic reactivity that can be mediated by enzymes, addressing a key bottleneck for their widespread adoption in industrial chemical synthesis. A key approach to this is building enzymes with unnatural catalytic components that provide an expanded palette with new possibilities for ...
Reuben B. Leveson‐Gower
wiley   +1 more source

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