Results 71 to 80 of about 1,785,581 (311)

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Septin-Associated Protein Kinases in the Yeast Saccharomyces cerevisiae [PDF]

Frontiers in Cell and Developmental Biology, 2016
Septins are a family of eukaryotic GTP-binding proteins that associate into linear rods, which, in turn, polymerize end-on-end into filaments, and further assemble into other, more elaborate super-structures at discrete subcellular locations. Hence, septin-based ensembles are considered elements of the cytoskeleton.
Perez, Adam M, Finnigan, Gregory C, Roelants, Françoise M, Thorner, Jeremy   +3 more
openaire   +5 more sources

Malic Acid Production by Saccharomyces cerevisiae: Engineering of Pyruvate Carboxylation, Oxaloacetate Reduction, and Malate Export [PDF]

, 2008
Malic acid is a potential biomass-derivable "building block" for chemical synthesis. Since wild-type Saccharomyces cerevisiae strains produce only low levels of malate, metabolic engineering is required to achieve efficient malate production with this ...
Van Maris, A.J.A. (author), Dijkema, C., Van Winden, W.A. (author), Winden, W.A., van, Dijkema, C. (author), Zelle, R.M. (author), Van Maris, A.J.A., Van Winden, W.A., De Hulster, E., Geertman, J.M., Pronk, J.T. (author), Hulster, E., de, Geertman, J.M.A., Winkler, A.A. (author), Van Dijken, J.P., Pronk, J.T., Winkler, A.A., De Hulster, E. (author), De Waard, P. (author), Geertman, J.M. (author), Waard, P., de, Zelle, R.M., De Waard, P., Van Dijken, J.P. (author)   +23 more
core   +2 more sources

Modulation of Lung Adenocarcinoma by Phosphorylated FOXN3‐Mediated Transcriptional Inactivation of p53

Advanced Science, EarlyView.
In non‐tumorous lung tissues, FOXN3 promotes the transcriptional activation of p53 by facilitating its recruitment to target promoters, thereby suppressing lung tumorigenesis through activation of the p53 signaling pathway. Conversely, in lung adenocarcinoma tissues, hyperphosphorylated FOXN3 dissociates from the promoters of p53‐responsive genes and ...
Jinjin Yu, Jingyu Yu, Suhui Wang, Xinghong Hu, Lele Jin, Nan Wu, Yuhan Ni, Xueying Zhang, Chengling Zhao, Jihong Zhou, Yong Zhang, Baofa Sun, Hongxing Zhang, Chunfu Zheng, Song Guo Zheng, Wei Li, Xinxing Zhu   +16 more
wiley   +1 more source

A Consensus of Core Protein Complex Compositions for Saccharomyces cerevisiae [PDF]

Molecular Cell, 2010
Analyses of biological processes would benefit from accurate definitions of protein complexes. High-throughput mass spectrometry data offer the possibility of systematically defining protein complexes; however, the predicted compositions vary substantially depending on the algorithm applied.
Benschop, Joris J., Brabers, Nathalie, van Leenen, Dik, Bakker, Linda V., van Deutekom, Hanneke W. M., van Berkum, Nynke L., Apweiler, Eva, Lijnzaad, Philip, Holstege, Frank C. P., Kemmeren, Patrick   +9 more
openaire   +4 more sources

Characterising Maturation of GFP and mCherry of Genomically Integrated Fusions in Saccharomyces cerevisiae

Bio-Protocol, 2018
Single-molecule fluorescence microscopy enables unrivaled sub-cellular quantitation of genomically encoded fusions of native proteins with fluorescent protein reporters.
Sviatlana Shashkova, Adam Wollman, Stefan Hohmann, Mark C Leake   +3 more
doaj   +1 more source

Saccharomyces cerevisiae as a superior host for overproduction of prokaryotic integral membrane proteins

Current Research in Structural Biology, 2021
Integral membrane proteins (IMPs) constitute ~30% of all proteins encoded by the genome of any organism and Escherichia coli remains the first-choice host for recombinant production of prokaryotic IMPs.
Sarah Spruce Preisler, Anders Drabaek Wiuf, Marc Friis, Lasse Kjaergaard, Molly Hurd, Eva Ramos Becares, Casper Normann Nurup, Frederik Bühring Bjoerkskov, Zsófia Szathmáry, Pontus Emanuel Gourdon, Kirstine Calloe, Dan A. Klaerke, Kamil Gotfryd, Per Amstrup Pedersen   +13 more
doaj   +1 more source

Subversion of Atypical Mucin Traps by a Spore‐Coat Effector Blocks Cellular Immunity in Drosophila

Advanced Science, EarlyView.
While the entomopathogenic fungus Metarhizium robertsii can evade insect humoral immunity, its subversion of cellular defenses is still elusive. We identify Eac1 as a spore‐coat protein essential for infecting drosophilids by targeting atypical mucins (Sgf1 and Sgf2), which can entrap spores in a gel matrix and thereby facilitate hemocyte encapsulation.
Shiqin Li, Haimin Chen, Gangqi Fang, Dongxiang Wei, Hongyun Wu, Chen Chen, Song Hong, Chengshu Wang   +7 more
wiley   +1 more source

Herbicide Metabolic Resistance in Poaceae Plants via the GA‐GID1/DELLA‐DOF2‐P450s Module

Advanced Science, EarlyView.
Plant hormone signaling modulates herbicide resistance in Echinochloa crus‐galli. The GA–DELLA–DOF2 cascade directly activates P450 detoxification genes in two Poaceae species, uncovering a core mechanism of metabolic herbicide resistance. ABSTRACT Barnyard grass (Echinochloa crus‐galli) is one of the world's most important weeds, and the evolution of ...
Junzhi Wang, Jiale Qi, Lin Wei, Qin Yu, Zhongyuan Liu, Lianyang Bai, Lang Pan   +6 more
wiley   +1 more source

Characterization of Fluorescent Proteins for Three- and Four-Color Live-Cell Imaging in S. cerevisiae.

PLoS ONE, 2016
Saccharomyces cerevisiae are widely used for imaging fluorescently tagged protein fusions. Fluorescent proteins can easily be inserted into yeast genes at their chromosomal locus, by homologous recombination, for expression of tagged proteins at ...
Ryo Higuchi-Sanabria, Enrique J Garcia, Delia Tomoiaga, Emilia L Munteanu, Paul Feinstein, Liza A Pon   +5 more
doaj   +1 more source