Results 91 to 100 of about 155,571 (316)

Linking Genotype and Phenotype of Saccharomyces cerevisiae Strains Reveals Metabolic Engineering Targets and Leads to Triterpene Hyper-Producers [PDF]

, 2011
Background: Metabolic engineering is an attractive approach in order to improve the microbial production of drugs. Triterpenes is a chemically diverse class of compounds and many among them are of interest from a human health perspective.
Otero, Jose M., Otero, JM, Koetter, P, Jens Nielsen, Semba, Saori, Tetsuo Kushiro, Karina M Madsen, Nielsen, Jens B, Ebizuka, Yutaka, Jose M. Otero, Kötter, Peter, Gupta D. B. R. K. Udatha, Udatha, Gupta D. B. R. K., Semba, S, Yutaka Ebizuka, Otero Jose M., Jose M Otero, Nielsen, Jens, Panagiotou, Gianni, Panagiotou Gianni, Nielsen, J, Panagiotou, G, Gianni Panagiotou, Madsen Karina M., Udatha Gupta D. B. R. K., Semba Saori, Udatha, Gupta, Madsen, KM, Ebizuka, Y, Madsen, Karina Marie, Madsen, Karina M., Karina M. Madsen, Saori Semba, Udatha, GDBRK, Koetter Peter, Otero, Jos\ue9 Manuel, Otero Romero, José Manuel, Kushiro Tetsuo, Gupta D B R K Udatha, Ebizuka Yutaka, Kushiro, Tetsuo, Koetter, Peter, Kushiro, T, Udatha, D.B.R.K. Gupta, Nielsen Jens, Nielsen, Jens B., Peter Koetter   +46 more
core   +1 more source

Changes in trehalose content of baker's yeast as affected by octanoic acid Alterações no teor de trealose de levedura de panificação provocadas por ácido octanóico

Scientia Agricola, 1993
Octanoic acid inhibited ethanolic fermentation by Saccharomyces cerevisiae (bakers yeast) and the trehalose accumulation, however did not affect the endogenous degradation of trehalose.
L.E. Gutierrez
doaj   +1 more source

Engineered Optogenetic Circuits In Yeast with Self‐Sustained Outputs

Advanced Science, EarlyView.
Optogenetic quorum‐sensing (OptoQS) circuit enables Saccharomyces cerevisiae to record transient light stimulus with self‐sustained outputs. Panel a indicates the design of the OptoQS circuit based on G‐protein coupled receptor (GPCR) signaling cascade. Panel b indicates the mode of action of surrogate messenger‐mediated signal transmission at the cell
Cong Fan, Haofeng Chen, Yan Wang, Junyi Wang, Yueyang Chen, Yang Zhang, Jinting Guan, Jifeng Yuan   +7 more
wiley   +1 more source

Study of the regulation of Fab1p, a phosphatidylinositol 3-phosphate 5 kinase in Saccharomyces cerevisiae.

, 2005
The Saccharomyces cerevisiae protein Fab1p is the archetypal type III phosphatidyl inositol phosphate kinase. This family of enzymes is universal to all eukaryotes and is responsible for the synthesis of phosphatidylinositol 3,5-bisphosphate from ...
Phelan, J.P., Phelan, John Paul
core  

Phosphorylation events surrounding the DNA damage response in "Saccharomyces cerevisiae" [PDF]

, 2007
Protein phosphorylation mediated by checkpoint kinases is crucial for the cellular response to DNA damage. The sensor kinases Mec1 and Tel1 initiate the checkpoint signaling cascade by directly activating the checkpoint effector kinase Rad53.
Schleker, Thomas Andreas
core   +1 more source

Tor1 regulates protein solubility in Saccharomyces cerevisiae

Molecular Biology of the Cell, 2012
Accumulation of insoluble protein in cells is associated with aging and aging-related diseases; however, the roles of insoluble protein in these processes are uncertain. The nature and impact of changes to protein solubility during normal aging are less well understood.
Peters, Theodore W., Rardin, Matthew J., Czerwieniec, Gregg, Evani, Uday S., Reis-Rodrigues, Pedro, Lithgow, Gordon J., Mooney, Sean D., Gibson, Bradford W., Hughes, Robert E.   +8 more
openaire   +2 more sources

SuFEx‐Enabled Reprogramming of Flavonoids for Selective α‐Glucosidase Covalent Inhibition

Advanced Science, EarlyView.
Selective inhibition of intestinal α‐glucosidase remains limited by poor enzyme specificity and off‐target metabolic effects. Here, SuFEx click chemistry is used to reprogram natural flavonoids into covalent inhibitors with enhanced α‐glucosidase selectivity and controlled reactivity. This strategy enables effective regulation of carbohydrate digestion
Fengyu Guo, Liwei Zhang, Minlong Wang, Yanjin Du, Tianyu Zhang, Hao Chen, Jiazeng Sun, Yang Yu, Zude He, Jie An, Xiaoxu Zhang, Weilin Lin, Fazheng Ren, Pengjie Wang, Ping Liu   +14 more
wiley   +1 more source

Identification and functional characterisation of a class on non-selective cation channels in Saccharomyces cerevisiae. [PDF]

, 2009
Na⁺ accumulation is a significant component in salt toxicity in plants. Although many proteins that facilitate Na⁺ flux have been identified in plants, investigations aimed at identifying the initial mechanism of Na⁺ entry into plants have failed.
Carter, Scott Anthony William
core  

Contributions of ubiquitin- and PCNA-binding domains to the activity of Polymerase η in Saccharomyces cerevisiae

, 2007
Bypassing of DNA lesions by damage-tolerant DNA polymerases depends on the interaction of these enzymes with the monoubiquitylated form of the replicative clamp protein, PCNA.
Bielen, Aleksandra B., Ulrich, Helle D., Parker, Joanne L., Đikić, Ivan   +3 more
core   +1 more source

Cells expressing murine RAD52 splice variants favor sister chromatid repair [PDF]

, 2006
The RAD52 gene is essential for homologous recombination in the yeast Saccharomyces cerevisiae. RAD52 is the archetype in an epistasis group of genes essential for DNA damage repair.
Freeman, TC, Savitzky, MH, Sunjevaric, [No Value], Rothstein, R, Marrero, VA, Thorpe, PH   +5 more
core   +1 more source