Results 1 to 10 of about 243 (118)
Optimized AAV Vectors for TMC1 Gene Therapy in a Humanized Mouse Model of DFNB7/11
Biomolecules, 2022 Gene therapy for genetic hearing loss is an emerging therapeutic modality for hearing restoration. However, the approach has not yet been translated into clinical application.
Irina Marcovich +5 more
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Marine Ecology, EarlyView., 2023 Abstract Microplastic input into the ocean represents an increasing threat to marine biota and may endanger the functioning of marine ecosystems, especially in semi‐enclosed basins, such as the Mediterranean Sea. The size spectrum of microplastics overlaps with that of nano‐microplankton (2–200 μm), thus potentially misleading suspension‐feeding ...
Claudia Traboni +3 more
wiley +1 more source
Case Report: Isolated Idiopathic Saccular Dysfunction
Frontiers in Neurology, 2021 Advances in vestibular testing have now allowed us to test each semicircular canal as well as the utricle and saccule, independently. This has led to the discovery of new patterns of vestibular dysfunction that were once impossible to evaluate.
Sofia Waissbluth, Javier Oyarzún
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Efficient Viral Transduction in Fetal and Adult Human Inner Ear Explants with AAV9-PHP.B Vectors
Biomolecules, 2022 Numerous studies have shown the recovery of auditory function in mouse models of genetic hearing loss following AAV gene therapy, yet translation to the clinic has not yet been demonstrated.
Edward S. A. van Beelen +10 more
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Frontiers in Neurology, 2022 ObjectiveThis study aims to investigate the potential vestibular pathway impairment through vestibular evoked myogenic potentials (VEMPs) and to explore the pathophysiological significance of these instrument-based findings in children with recurrent ...
Xiayu Sun +33 more
doaj +1 more source
Frontiers in Neurology, 2020 Sudden sensorineural hearing loss (SSNHL) patients with vertigo have a poorer prognosis. However, the factors associated with hearing recovery remain uncertain.
Yixu Wang +4 more
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Frontiers in Integrative Neuroscience, 2023 IntroductionCervical vestibular evoked myogenic potentials (cVEMPs) provide an objective measure of the integrity of the sacculo-collic pathway leading to their widespread use as a clinical tool in the diagnostic vestibular test battery.
Federica M. Raciti +8 more
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Cervical Vestibular-Evoked Myogenic Potentials in Sedated Toddlers
International Archives of Otorhinolaryngology, 2017 Introduction Cervical vestibular-evoked myogenic potentials (cVEMPs) are difficult to test in toddlers who cannot follow instructions or stay calm. Objective Due to the growing need for vestibular testing in very young children as a part of ...
Ola Abdallah Ibraheem +1 more
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Frontiers in Neurology, 2019 Objective: The objective of our study was to investigate the potential association between the occurrence of benign paroxysmal positional vertigo (BPPV) and saccular dysfunction using cervical vestibular evoked myogenic potentials (cVEMP) testing.Methods:
Gang Chen +5 more
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Transcription factor Emx2 controls stereociliary bundle orientation of sensory hair cells
eLife, 2017 The asymmetric location of stereociliary bundle (hair bundle) on the apical surface of mechanosensory hair cells (HCs) dictates the direction in which a given HC can respond to cues such as sound, head movements, and water pressure.
Tao Jiang, Katie Kindt, Doris K Wu
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