Results 181 to 190 of about 38,379 (270)

Pre‐analytical guidelines for blood and CSF Biomarkers 2025: Recommendations from the NACC ADRC Biofluid Biomarker Best Practices Workgroup

open access: yesAlzheimer's &Dementia, Volume 22, Issue 5, May 2026.
Abstract The Biofluid Biomarkers Best Practices Workgroup of the National Alzheimer's Coordinating Center–Alzheimer's Disease Research Center (ADRC) Biomarker Core Steering Committee was convened to update pre‐analytical handling guidelines for biofluid biomarkers, focusing on cerebrospinal fluid (CSF) and blood.
Timothy E. Van Meter   +21 more
wiley   +1 more source

Association between proximity to a lead‐releasing facility and cognition in diverse cohorts

open access: yesAlzheimer's &Dementia, Volume 22, Issue 5, May 2026.
Abstract BACKGROUND The associations between adult lead exposure and late‐life cognition are largely unknown. METHODS In two cohorts, Kaiser Healthy Aging and Diverse Life Experiences (KHANDLE, n = 1638) and Study of Healthy Aging in African Americans (STAR, n = 741), we assessed residential proximity to lead‐releasing facilities for association with ...
Scarlet Cockell   +9 more
wiley   +1 more source

Abi3S212F Alzheimer's disease variant alters plaque structure and disrupts microglia

open access: yesAlzheimer's &Dementia, Volume 22, Issue 5, May 2026.
Abstract BACKGROUND Genetic variants affecting microglial function can influence Alzheimer's disease (AD) risk, yet the underlying mechanisms remain unclear. The AD‐associated ABI3S209F (Abi3S212F in mouse) variant regulates cytoskeletal dynamics, but its in vivo impact on pathology is unknown. METHODS: An Abi3S212F mouse was developed and crossed with
Claire A. Butler   +29 more
wiley   +1 more source

Effects of α‐synuclein pathology on synaptic dysfunction and clinical outcomes in normal aging

open access: yesAlzheimer's &Dementia, Volume 22, Issue 5, May 2026.
Abstract INTRODUCTION α‐Synuclein is the hallmark pathology of Parkinson's disease and dementia with Lewy bodies, described together as Lewy body disease (LBD). We investigated effects of α‐syn biomarker positivity in clinically unimpaired (CU) individuals.
Joseph R. Winer   +22 more
wiley   +1 more source

Black in Impressionism and Post‐Impressionism: Art, Color Vision, and Psychophysics

open access: yesColor Research &Application, Volume 51, Issue 3, May/June 2026.
Black has engendered controversy in 19th Century color theory and in Impressionist and Post‐Impresssionist painting. The neural mechanisms of blackness perception are being revealed through contemporary psychophysics. ABSTRACT From Paleolithic cave art to modern abstraction, artists have used black not merely as a neutral tone, but as a powerful ...
John S. Werner
wiley   +1 more source

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