Results 41 to 50 of about 8,661 (273)

HIERARCHIC SKELETAL ORGANIZATION – A FACTOR REGULATING THE STRUCTURE OF FATIGUE INJURIES. PART III. MODELING THE INITIAL STAGE OF THEIR DEVELOPMENT

Travmatologiâ i Ortopediâ Rossii, 2011
The authors describe general conditions of fatique injuries (FI) initiation and development, and discuss the conformity between hierarchic skeletal organization levels and spatial differentiation of the initial FI types – local discrete and local ...
A. S. Avrunin, R. M. Tikhilov, I. K. Parshin, B. E. Melnikov   +3 more
doaj   +1 more source

Misogyny in Women's Literature: A Comparative Study of Jane Austen's Pride and Prejudice and Zoya Pirzad's I'll Turn off the Lights [PDF]

ادبیات تطبیقی, 2020
1. Introduction Misogyny is a universal phenomenon defined as the hatred of women manifest in the social and cultural practices and in the rites, rituals and literature of different societies.
Nahid Fakhrshafaie
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Molecular Structures and Intermolecular Hydrogen Bonding of Silylated 2-Aminopyrimidines

Crystals, 2023
A series of silylated 2-aminopyrimidines Me(4−n)Si(NHpyr)n (Me = methyl, NHpyr = pyrimid-2-ylamino, n = 1, 2, 3, 4), i.e., compounds 1, 2, 3, and 4, respectively, was prepared from a series of the respective chlorosilanes Me(4−n)SiCln and 2 ...
Marcus Herbig, Edwin Kroke, Jörg Wagler
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

A combined numerical and theoretical study on the strengthening and toughening mechanisms of double network hydrogels

International Journal of Smart and Nano Materials
Double network (DN) hydrogels, comprising two interpenetrating networks, exhibit superior mechanical strength and toughness compared to single-network hydrogels.
Bo Gong, Ji Lin, Yu Xie, Jin Qian
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Visible light photoredox-catalyzed deoxygenation of alcohols

Beilstein Journal of Organic Chemistry, 2014
Carbon–oxygen single bonds are ubiquitous in natural products whereas efficient methods for their reductive defunctionalization are rare. In this work an environmentally benign protocol for the activation of carbon–oxygen single bonds of alcohols towards
Daniel Rackl, Viktor Kais, Peter Kreitmeier, Oliver Reiser   +3 more
doaj   +1 more source

Bioinspired Engineering of Sacrificial Metal–Ligand Bonds into Elastomers with Supramechanical Performance and Adaptive Recovery

, 2016
Reinforcing rubbers and expanding their application galleries are two important issues in material science and engineering. In this work, we demonstrate a bioinspired design of high-performance and macroscopically responsive diene-rubber by engineering ...
Liqun Zhang (115900), Baochun Guo (1347801), Zhenghai Tang (1347807), Jing Huang (41604), Fang Liu (13271)   +4 more
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source