Results 31 to 40 of about 54,356 (248)

Starburst amacrine cells form gap junctions in the early postnatal stage of the mouse retina

open access: yesFrontiers in Cellular Neuroscience, 2023
Although gap junctional coupling in the developing retina is important for the maturation of neuronal networks, its role in the development of individual neurons remains unclear.
Takuma Maruyama   +2 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Inorganic clay-enhanced cellulose-based superabsorbent composites on swelling performance and responsive behavior

open access: yesIndustrial Crops and Products
The inorganic clay had a significant impact on the properties of superabsorbent composites (SACs). In this study, the alkali-urea system pretreated bamboo pulp fibers were used as raw material, acrylic acid (AA), acrylamide (AM) and 2-acrylamido-2-methyl-
Wenliang Wang   +5 more
doaj   +1 more source

Scientific Advisory Committees at the World Health Organization: A Qualitative Study of How Their Design Affects Quality, Relevance, and Legitimacy

open access: yesGlobal Challenges, 2018
Governments and international organizations frequently convene scientific advisory committees (SACs) to support decision‐making with scientific advice.
Unni Gopinathan   +2 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Evaluation of forces produced by therapeutic elastic resistance bands of various lengths and stiffnesses: a biomechanical study for clinical application

open access: yesFrontiers in Veterinary Science
IntroductionElastic resistance bands (ERBs) are commonly incorporated into canine and human strengthening exercises to restore muscle strength during rehabilitation; however, there is limited published quantitative data regarding force production under ...
Phillip Saint-Martin   +4 more
doaj   +1 more source

Recent progresses on single-atom catalysts for the removal of air pollutants

open access: yesFrontiers in Chemistry, 2022
The booming industrialization has aggravated emission of air pollutants, inflicting serious harm on environment and human health. Supported noble-metals are one of the most popular catalysts for the oxidation removal of air pollutants. Unfortunately, the
Yang Wang, Yang Wang, Min Wang, Min Wang
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Joan Brull : evocació d'un pintor barceloní del temps del modernisme [PDF]

open access: yes, 1924
Opuscle sobre el pintor Joan Brull escrit per Joan Sacs i publicat a Barcelona l'any 1924.Opúsculo sobre el pintor Joan Brull escrito por Joan Sacs y publicado en Barcelona en 1924.Opuscle about the painter Joan Brull written by Joan Sacs and published ...
Fons Sebastià Sánchez-Juan (Universitat Autònoma de Barcelona)   +1 more
core   +1 more source

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