Results 91 to 100 of about 339,904 (294)
Advanced Science, EarlyView.The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving
Valentina Davi +13 more
wiley +1 more source
Theories of Gold Price Movements: Common Wisdom or Myths? [PDF]
, 2010 This paper examines several of the explanations commonly provided regarding gold and its price movements. We consider the safe haven, inflation hedge, and dollar destruction hypotheses. The results are mixed.
Adibe, Kelechi, Fei, Fan
core +1 more source
Bacterial Outer Membrane Vesicles in Potentiating Cancer Vaccines: Progress and Prospects
Advanced Science, EarlyView.Bacterial outer membrane vesicles (OMVs) have emerged as versatile platforms for cancer vaccine development owing to their intrinsic immunostimulatory properties and high engineering flexibility. This review summarizes OMV biology, immune mechanisms, and engineering strategies that enhance vaccine efficacy, discusses key translational challenges, and ...
Jiabeini Zhang +9 more
wiley +1 more source
A colony provides a safe haven [PDF]
For the Contingency of Curation conference we explored new ways of presenting the traditional paper to a conference by creating a sound work. The original content of the presentation was Host Artists Group (H.A.G.) text* written for S.H.U.'s Transmission
Webb, Neil, Wright, Ron
core
, 2015 IMPACT. 1: Educated approximately 200 professionals and trainees -- 2. Visited with nearly 300 CHOICES residents -- 3. Collaborated with over 6 organizations and colleges, including The Center for Family Safety and Healing and the College of Social Work.
Dent, Colleen Shockling
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A Survey of Techniques for Improving Security of GPUs
, 2018 Graphics processing unit (GPU), although a powerful performance-booster, also has many security vulnerabilities. Due to these, the GPU can act as a safe-haven for stealthy malware and the weakest `link' in the security `chain'.
Abhinaya, S. B. +3 more
core +1 more source
Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy
Advanced Science, EarlyView.Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu +4 more
wiley +1 more source
Gold and financial assets: Are there any safe havens in bear markets? [PDF]
This paper looks into the role of gold as a safe haven or a hedge against stocks. We extend the existing literature in two ways. First, we consider crisis periods successively defined by recessions and bear markets.
Hélène Raymond-Feingold +1 more
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Operational Manoeuvre Group: Operation SOHIL LARAM II, Kandahar Province, February 2008 [PDF]
, 2012 In February 2008 Regional Battle Group (South) in Afghanistan, based on The 1st Battalion, The Royal Gurkha Rifles supported by Canadian “enablers” and working with Afghan national security forces, conducted a mission known as Operation SOHIL LARAM II in
Maloney, Sean M.
core +1 more source
Advanced Science, EarlyView.This study reports the development of a fully humanized bispecific T cell engager targeting IL13RA2, a tumor‐associated antigen enriched in glioblastoma. This off‐the‐shelf immunotherapy drives potent, antigen‐dependent T cell activation and tumor killing, and prolongs survival in experimental GBM and other solid tumors models without detectable off ...
Joseph T. Duffy +16 more
wiley +1 more source