Results 71 to 80 of about 339,904 (294)
Safe Haven vs. Earnings Stripping Rules: a Prisoner Dilemma? [PDF]
, 2015 Internal debt financing can be used by multinational firms to shift profits from high-tax to low-tax countries. Governments apply thin capitalization rules (TCRs), which limit the deductibility of interest expenses, to restrict this behavior.
Kalamov, Zarko Y.
core
Advanced Science, EarlyView.The butterfly unfolded wing in an open form structure of botulinum neurotoxin type A (BoNT/A) at physiological‐state was confirmed at 2.85 Å resolution by cryo‐electron microscopy (cryo‐EM). Structure‐guided protein engineering significantly enhanced the receptor‐binding affinity, therapeutic efficacy, and safety of the engineered toxin variants ...
Wenrui Wang +16 more
wiley +1 more source
Optimal risk computation on precious metal’s assets diversification [PDF]
, 2018 Optimization is the selection of a best element with regards to certain criterion from set of available alternatives. This paper investigates the effects of assets in optimizing risk using diversification strategy and also examines gold quality of ...
Is-Moen, Muhaimin +6 more
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Localized NF‐κB Inhibition Reduces Lipid Nanoparticle‐Associated Inflammation
Advanced Science, EarlyView.Lipid nanoparticles (LNPs) activate NF‐κB and provoke inflammation that limits therapeutic delivery. By encapsulating selective NF‐κB inhibitors within LNPs, localized suppression of inflammatory signaling is achieved without compromising mRNA expression.
Carolann L. Espy +16 more
wiley +1 more source
We study high-frequency exchange rate movements over the sample 1993-2006. We document that the (Swiss) franc, euro, Japanese yen and the pound tend to appreciate against the U.S. dollar when (a) S&P has negative returns; (b) U.S.
Angelo Ranaldo, Paul Söderlind
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Advanced Science, EarlyView.This study reveals the molecular mechanism by which the transcription factor FgSge1 regulates mycotoxin biosynthesis and virulence in Fusarium graminearum. FgSge1 binds to the TAARGTTT cis‐element, enabling self‐activation. It recruits the SAGA complex, promotes histone acetylation, and facilitates jet‐like chromatin remodeling, thereby activating ...
Yueqi Zhang +6 more
wiley +1 more source
Advanced Science, EarlyView.ABSTRACT Base editors enable precise genome modification and have emerged as a promising therapeutic approach for correcting diseases caused by single‐nucleotide variants. While the current efficient version of adenine base editors (ABEs), such as ABE8e, exhibits exceptional efficiency for A‐to‐G conversions, their clinical translation is hindered by ...
Jiawei Yao +12 more
wiley +1 more source
The US dollar: Safe haven - Despite rising US current account deficit [PDF]
The empirical analysis in this paper supports the view that the status of the US dollar as a “safe haven” is closely related to the development of the US current account and the US net foreign debt.
Diekmann, Berend, Meurers, Martin
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The US dollar: Safe haven - Despite rising US current account deficit [PDF]
, 2007 The empirical analysis in this paper supports the view that the status of the US dollar as a “safe haven” is closely related to the development of the US current account and the US net foreign debt.
Diekmann, Berend, Meurers, Martin
core
Macrophage Extracellular Traps in Immunity and Cancer
Advanced Science, EarlyView.As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li +5 more
wiley +1 more source