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, 2016 In recognizing the classroom as a space of vulnerability, the concept of “safe space” has proven helpful yet also potentially problematic. Because what is safe for some is certainly not for others and because “safety” can be a privilege to which not all have access, can safe spaces exist?
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New ScientistSafe Space reflects upon the ways in which racism creeps into classrooms and makes itself known despite teachers' best efforts to prevent it from invading the safe space they attempt to create.
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A safe operating space for humanity [PDF]
Nature, 2009 Identifying and quantifying planetary boundaries that must not be transgressed could help prevent human activities from causing unacceptable environmental change, argue Johan Rockstrom and colleagues.
Rockström, J. +28 more
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FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
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What makes a space safe? Consumers' perspectives on a mental health safe space
International Journal of Mental Health Nursing, 2023 AbstractThe provision of community‐based space for people experiencing a mental health crisis is regarded as a favourable alternative to the emergency department. However, the only non‐emergency department safe spaces in Western Australia are located within hospitals or hospital grounds.
Lesley Andrew +5 more
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FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
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Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Closure conversion is safe for space [PDF]
Proceedings of the ACM on Programming Languages, 2019 We formally prove that closure conversion with flat environments for CPS lambda calculus is correct (preserves semantics) and safe for time and space, meaning that produced code preserves the time and space required for the execution of the source program.
Zoe Paraskevopoulou, Andrew W. Appel
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Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
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FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
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