Results 111 to 120 of about 19,708 (243)
Advanced Science, EarlyView.A novel exercise‐inducible myokine acidic ribosomal protein P2 (RPLP2), initially identified from human trials, is presented here, whose circulating levels negatively correlate with clinical anxiety severity. Muscle‐derived RPLP2 enhances hippocampal ribosomal assembly and adult neurogenesis to rescue stress‐induced anxiety deficits.
Peiyu Luo +18 more
wiley +1 more source
Detection and categorization of suggestive thumbnails : A step towards a safer internet
, 2021 The aim of this work is to compare methods that predict whether an image has suggestive content, such as pornographic images and erotic fashion. Using binary classification, this work contributes to an internet environment where these images are not seen out of context. It is, therefore, necessary for user experience improvement purposes, such as child
openaire +1 more source
Advanced Science, EarlyView.Orally administered, pH‐responsive Co‐SAN exerts dual functions: in the alkaline intestinal milieu, it scavenges reactive oxygen species (ROS) and suppresses the PI3K/AKT pathway and NETs formation, thus providing radioprotection; whereas in the acidic tumor microenvironment, it generates ROS and alleviates hypoxia, thereby enhancing radiosensitization.
Shengqi Yin +13 more
wiley +1 more source
You Can't Launch This: Trust as Infrastructure in Digital Behavioral Health. [PDF]
J Med Internet Resvan Mierlo T.
europepmc +1 more source
Automation and Active Learning for the Multi‐Objective Optimization of Antibody Formulations
Advanced Science, EarlyView.Successful antibody formulation necessitates balancing factors such as thermal stability, colloidal stability, and viscosity across a vast excipient design space. This work integrates robotic liquid handling, high‐throughput biophysical characterization, and multi‐objective Bayesian optimization in an iterative closed‐loop Design‐Build‐Test‐Learn cycle.
D. Christopher Radford +3 more
wiley +1 more source
Printing Personalized Medicine: 3D Models Bring Better Surgical Outcomes. [PDF]
J Med Internet ResCongdon J.
europepmc +1 more source
Advanced Science, EarlyView.Polydopamine nanoparticles enable a precise, non‐genetic, and transcranial neuromodulation strategy via near‐infrared photothermal stimulation. By activating TRPV1 channels, this approach specifically enhances hippocampal gamma oscillations, thereby rescuing spatial memory deficits in models of perioperative neurocognitive disorder.
Yan‐Bo Zhou +10 more
wiley +1 more source
How Digital Diaries Are Changing Communication and Recovery in the Intensive Care Unit and Beyond. [PDF]
J Med Internet ResCongdon J.
europepmc +1 more source
A Molten Salt Extraction Method for Palladium Recovery via the CaPd2 Intermetallic Compound
Advanced Science, EarlyView.A designed Ca → CaPd2 → Pd pathway enables acid–free palladium recovery in molten salt. Calcium alloying forms anionic CaPd2, which is selectively oxidized by iodine from CaI2 to yield high–purity metallic Pd. ABSTRACT To address palladium scarcity and the low efficiency of conventional recovery processes, this work presents a molten–salt extraction ...
Jiapeng Zhang +6 more
wiley +1 more source