Results 231 to 240 of about 1,045,655 (263)
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Ponatinib: A Review of Efficacy and Safety
Current Cancer Drug Targets, 2018Ponatinib is a third generation kinase inhibitor designed to overcome the gatekeeper T315I mutation. In different trials this drug showed inhibitory activity against native BCR-ABL1 kinase and several ABL1 mutations. For this reason, ponatinib is currently indicated for the treatment of chronic myeloid leukaemia (CML) in every phase of disease ...
Massaro F, Molica M, Breccia M
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Pixantrone: merging safety with efficacy
Expert Review of Hematology, 2013Pixantrone is a novel anthracycline derivative, manufactured by Cell Therapeutics Incorporated, WA, USA. It was developed with the aim to retain the efficacy of anthracyclines and be less cardiotoxic. Initial safety trials and single-arm, Phase II trials have shown preliminary evidence of anticancer activity and manageable toxicity.
Dionysios, Papadatos-Pastos +1 more
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Concentrate safety and efficacy
Haemophilia, 2002Safety from transmission of infections through plasma‐derived clotting factor concentrates is assured by improved donor screening, serological testing of individual donations and direct viral testing of small plasma pools. Modern viral‐inactivation techniques are highly effective.
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Efficacy and Safety of Percutaneous Epiphysiodesis
Journal of Pediatric Orthopaedics, 2008The aims of this study were to evaluate outcomes of percutaneous epiphysiodesis, as described by Bowen, in 97 patients and to assess complications and determine whether the effect of the epiphysiodesis will accurately follow the Moseley chart predictions.A total of 97 patients were reviewed retrospectively.
Muharrem, Inan +4 more
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Metrifonate: Overview of Safety and Efficacy
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 1998Metrifonate is a cholinesterase inhibitor with a long‐lasting inhibition that raises brain acetylcholine levels. It is well‐absorbed and has limited binding to serum proteins. In preliminary studies of its utility in the treatment of Alzheimer disease's (AD), it led to improvements of cognition or reduced the rate of decline of cognition compared with ...
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Safety and Efficacy of Leadless Pacemakers: A Systematic Review and Meta‐Analysis
Journal of the American Heart Association, 2021Linh Ngo, Daniel Nour, Russell Denman
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The Safety and Efficacy of Phage Therapy: A Systematic Review of Clinical and Safety Trials
Antibiotics, 2022Helen J Stacey +2 more
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A comprehensive analysis of the efficacy and safety of COVID-19 vaccines
Molecular Therapy, 2021Yinghui Peng, Ping Liu, Cao Guo
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COVID-19 Vaccines: A Review of the Safety and Efficacy of Current Clinical Trials
Pharmaceuticals, 2021Zhipeng Yan +2 more
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