Results 121 to 130 of about 3,040,361 (309)

Analysis of nuclear waste disposal in space, phase 3. Volume 1: Executive summary of technical report [PDF]

open access: yes
The objectives, approach, assumptions, and limitations of a study of nuclear waste disposal in space are discussed with emphasis on the following: (1) payload characterization; (2) safety assessment; (3) health effects assessment; (4) long-term risk ...
Friedlander, A. L.   +4 more
core   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

Protecting the poor in Vietnam's emerging market economy [PDF]

open access: yes
Poverty Assessment,Environmental Economics&Policies,Rural Poverty Reduction,Safety Nets and Transfers,Services&Transfers to ...
Van de Walle, Dominique
core  

Why We Cannot (Yet) Ensure the Cybersecurity of Safety-Critical Systems [PDF]

open access: yes, 2016
There is a growing threat to the cyber-security of safety-critical systems. The introduction of Commercial Off The Shelf (COTS) software, including Linux, specialist VOIP applications and Satellite Based Augmentation Systems across the aviation ...
Johnson, Christopher W.
core  

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Safety management status for genetically modified microorganism and related products used for food industry

open access: yesZhongguo shipin weisheng zazhi
Genetically modified microorganism (GMM), also known as recombinant DNA microorganism, means a micro-organism in which the genetic material has been altered in a way that does not occur naturally by mating and/or natural recombination.
HAN Xiaomin   +6 more
doaj   +1 more source

Alameda County Placement Risk Assessment Validation [PDF]

open access: yes, 2000
The Alameda County Probation Department was awarded a grant from the National Institute of Justice in 1998 to develop a risk assessment for probation placement cases.

core  

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

open access: yesAging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef   +2 more
wiley   +1 more source

CO2 pipelines material and safety considerations [PDF]

open access: yes, 2009
This paper presents an overview of some of the most important factors and areas of uncertainty affecting integrity and accurate hazard assessment of CO2 pipelines employed as part of the Carbon Capture and Sequestration (CCS) chain.
Bilio, M   +4 more
core  

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin   +2 more
wiley   +1 more source

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