Results 11 to 20 of about 8,110,163 (275)

Safety Assessment of 2D MXenes: In Vitro and In Vivo

Nanomaterials, 2022
MXenes, representing a new class of two-dimensional nanomaterial, have attracted intense interest in a variety of fields as supercapacitors, catalysts, and sensors, and in biomedicine.
Jialong Wu, Yanyan Yu, Gaoxing Su
semanticscholar   +1 more source

Whole Genome Analysis of Three Multi-Drug Resistant Listeria innocua and Genomic Insights Into Their Relatedness With Resistant Listeria monocytogenes

Frontiers in Microbiology, 2021
Listeria innocua are Gram-positive rod-shaped bacteria, which are not generally infectious as opposed to Listeria monocytogenes. However, the comparatively high genomic similarity between both along with on occasion, their coexistence in similar ...
Menghan Li, Shaofei Yan, Séamus Fanning, Séamus Fanning, Fengqin Li, Jin Xu   +5 more
doaj   +1 more source

Survey on Scenario-Based Safety Assessment of Automated Vehicles

IEEE Access, 2020
When will automated vehicles come onto the market? This question has puzzled the automotive industry and society for years. The technology and its implementation have made rapid progress over the last decade, but the challenge of how to prove the safety ...
Stefan Riedmaier, Thomas Ponn, D. Ludwig, B. Schick, Frank Diermeyer   +4 more
semanticscholar   +1 more source

3D cell culture models: Drug pharmacokinetics, safety assessment, and regulatory consideration

Clinical and Translational Science, 2021
Nonclinical testing has served as a foundation for evaluating potential risks and effectiveness of investigational new drugs in humans. However, the current two‐dimensional (2D) in vitro cell culture systems cannot accurately depict and simulate the rich
Hongbing Wang, Paul C. Brown, E. Chow, L. Ewart, S. Ferguson, S. Fitzpatrick, Benjamin S. Freedman, G. Guo, W. Hedrich, S. Heyward, J. Hickman, N. Isoherranen, Albert P. Li, Qi Liu, S. Mumenthaler, J. Polli, W. Proctor, A. Ribeiro, Jian-Ying Wang, R. Wange, Shiew-Mei Huang   +20 more
semanticscholar   +1 more source

CCL2-CCR2 axis recruits tumor associated macrophages to induce immune evasion through PD-1 signaling in esophageal carcinogenesis

Molecular Cancer, 2020
Background The poor prognosis of esophageal squamous cell carcinoma (ESCC) highlights the need for novel strategies against this disease. Our previous study suggested the involvement of CCL2 and tumor associated macrophages (TAMs) in esophageal ...
Hui Yang, Qiannan Zhang, Miao Xu, Lei Wang, Xuewei Chen, Yongquan Feng, Yongning Li, Xin Zhang, Wenming Cui, Xudong Jia   +9 more
doaj   +1 more source

Suspended hydrogel culture as a method to scale up intestinal organoids

Scientific Reports, 2023
Primary tissue-derived epithelial organoids are a physiologically relevant in vitro intestinal model that have been implemented for both basic research and drug development applications.
Julia Y. Co, Jessica A. Klein, Serah Kang, Kimberly A. Homan   +3 more
doaj   +1 more source

Safety Assessment of Rehabilitation Robots: A Review Identifying Safety Skills and Current Knowledge Gaps

Frontiers in Robotics and AI, 2021
The assessment of rehabilitation robot safety is a vital aspect of the development process, which is often experienced as difficult. There are gaps in best practices and knowledge to ensure safe usage of rehabilitation robots.
J. Bessler, Gerdienke B. Prange-Lasonder, L. Schaake, José F. Saenz, C. Bidard, I. Fassi, M. Valori, A. B. Lassen, J. Buurke   +8 more
semanticscholar   +1 more source

Meta analysis of heavy metal and pesticide pollution status of nine medicinal and edible substances

Zhongguo shipin weisheng zazhi, 2023
ObjectiveTo evaluate the heavy metal and pesticide pollution status of nine medicinal and edible substances， including Eucommia ulmoides leaves， Codonopsis pilosula， Cistanche deserticola， Dendrobium candidum， Astragalus membranaceus， Panax quinquefolium，
BAO Huihui, JI Xiaoning, WU Nan, TANG Yu, LI Minglu, LI Qi, CAO Pei, ZHANG Lei, LI Jianwen   +8 more
doaj   +1 more source

Assessing drug safety [PDF]

BMJ, 2005
EDITOR—Eaton reports that more surveillance of drugs is needed to protect the public.1 All drugs are dangerous, some may also be useful. If drug efficacy is easy to show, drug safety (low risk) is essentially unprovable: absence of demonstration of risk is not demonstration of absence.
openaire   +2 more sources

Clustering a Chemical Inventory for Safety Assessment of Fragrance Ingredients: Identifying Read-Across Analogs to Address Data Gaps

Chemical Research in Toxicology, 2020
A valuable approach to chemical safety assessment is the use of read-across chemicals to provide safety data to support the assessment of structurally similar chemicals.
M. Date, D. O'brien, D. Botelho, T. Schultz, D. Liebler, T. Penning, D. Salvito   +6 more
semanticscholar   +1 more source