Results 81 to 90 of about 7,446,317 (248)
FEBS Open Bio, EarlyView.Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source
Zhongguo shipin weisheng zazhiObjectiveTo review and compare regulatory requirements and compliance considerations for the use of human milk oligosaccharides （HMOs） in food for special medical purposes intended for infants across major jurisdictions， and to appraise the mechanistic ...
JIN Zheyu +7 more
doaj +1 more source
FEBS Open Bio, EarlyView.NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
Zhongguo shipin weisheng zazhiObjectiveTo explore the species-level distribution and antimicrobial resistance of Cronobacter spp. isolated from condiments and cereal-based foods across 19 provinces （autonomous regions， municipalities） in China， and provide data support for analyzing ...
LI Menghan +5 more
doaj +1 more source
Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
FEBS Open Bio, EarlyView.We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source
Other title: State of Connecticut traffic records assessment, April 22-27, 2012
, 2012 "The National Highway Traffic Safety Administration (NHTSA) assembled a team to conduct a traffic records assessment in response to a request from the Highway Safety Office (HSO) in the Bureau of Policy and Planning of the Connecticut Department of ...
United States. Technical Assessment Team,
core +1 more source
Antimicrobial resistance in breeding pigs in Germany – differences between 2015 and 2023
Porcine Health ManagementBackground Direct contact with their offspring during the first few weeks makes sows a potential source of resistant bacteria for fattening pigs and food products derived from pigs.
Bernd-Alois Tenhagen +4 more
doaj +1 more source
Alternaria toxins in various food marketed in China and dietary exposure assessment
Zhongguo shipin weisheng zazhiObjectiveTo investigate occurrence of alternaria toxins various food marketed in China， and to evaluate dietary exposure and their potential health risks.MethodsA total of 7 694 samples of 11 types foods， including wheat flour， bread， and tomato sauce ...
YANG Xin +6 more
doaj +1 more source
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source