Results 81 to 90 of about 3,072,572 (310)

Development of an efficient finite element model for the dynamic analysis of the train-bridge interaction [PDF]

, 2010
The design of high-speed railway bridges comprises a set of demands, from safety and serviceability aspects, to new types of equipment and construction solutions.
Azevedo, A., Calcada, R., Neves, Sérgio
core   +1 more source

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

A multilevel neo-institutional analysis of infection prevention and control in English hospitals: coerced safety culture change? [PDF]

, 2019
Despite committed policy, regulative and professional efforts on healthcare safety, little is known about how such macro-interventions permeate organisations and shape culture over time.
Antonsen S., Aten K., Berger P.L., Birgand G., Boltanski L., Braithwaite J., Charani E., Charles K., Creswell J.W., Cullen W.D., Cunliffe A., Department of Health, Department of Health, Department of Health, Dixon‐Woods M., Dixon‐Woods M., Fiol C.M., Flin R., Francis R., Gioia D.A., Greenwood R., Halligan M., Harrison S.H., Hatch M.J., Herepath A., Howard‐Grenville J., Institute of Medicine (IOM), Kaufman J., Kyratsis Y., Leape L.L., Martin J., McCarthy D., Meyer J.W., Phillips N., Powell W.W., Reason J., Reay T., Reay T., Reay T., Reiman T., Schein E.H., Scott W.R., Seo M., Sexton J.B., Singer S.J., Smits M., Sorra J., Strauss A., Swidler A., Swidler A., Szymczak J.E., Templeton S.‐K., Thornton P.H., Vincent C., Walshe K., Waring J., Waring J.J., Weber K., Weick K.E., Weick K.E., Yin R.K., Zilber T.B.   +61 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Risk of key pathogens of Enterobacteriaceae contamination in foods for infants and young children and implications for the revision of standards of China

Zhongguo shipin weisheng zazhi
The problem of food-borne illnesses due to microbial contamination of infant and young children foods is usually of international concern， and the unique character of the infant and young child population requires special and strict food safety ...
CHEN Xiao, YANG Shuran, LIU Jikai, GUO Ge, WANG Yeru, GAN Xin, XU Wenjing, YAN Shaofei, LI Hui, HAN Xiaomin, ZHAO Jianyun   +10 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Kaempferol Improves Exercise Performance by Regulating Glucose Uptake, Mitochondrial Biogenesis, and Protein Synthesis via PI3K/AKT and MAPK Signaling Pathways

Foods
Kaempferol is a natural flavonoid with reported bioactivities found in many fruits, vegetables, and medicinal herbs. However, its effects on exercise performance and muscle metabolism remain inconclusive.
Xiaoning Ji, Chaozheng Zhang, Jing Yang, Yaru Tian, Lijuan You, Hui Yang, Yongning Li, Haibo Liu, Deng Pan, Zhaoping Liu   +9 more
doaj   +1 more source

Environmental assessment overview [PDF]

, 1980
The assessment program has as its objectives: to identify the environmental issues associated with the SPS Reference System; to prepare a preliminary assessment based on existing data; to suggest mitigating strategies and provide environmental data and ...
Valentino, A. R.
core   +1 more source

Aquatic food security:insights into challenges and solutions from an analysis of interactions between fisheries, aquaculture, food safety, human health, fish and human welfare, economy and environment [PDF]

, 2016
Fisheries and aquaculture production, imports, exports and equitability of distribution determine the supply of aquatic food to people. Aquatic food security is achieved when a food supply is sufficient, safe, sustainable, shockproof and sound ...
AB Associates, Agnew D.J., Allison E.H., Anon, Anon, Bagnis R., Black K.D., Braithwaite V., CDC, EA, FSA, NIEA, NRW and SEPA, EC, EC, EC, EC, EC, EC, EC, EC, EC, EC, EC, EC, EC, Ellis T., Enghoff I.B., European Food Safety Authority, European Market Observatory for Fisheries and Aquaculture Products, FAO, FAO, FAO, FAO, FAO, Farm Animal Welfare Committee, FDA, Food Standards Agency, Garcia S.M., Gil A., Hall S.J., Hallegraef G.M., Hart P.J., Health and Safety Executive, Health and Safety Executive, Higman W.A., Hixson S.M., ICES, IMF, International Labour Organisation, James M.A., Lambie‐Mumford H., Lambooija E., Maritime Accident Investigation Branch, Morgan O., National Crime Agency, National Toxicology Program, Neil D., Nesheim M.C., Papworth G.P., PHE‐FSA, Robb D.F.H., Roberts S.E., Roth B., Sainsbury's Supermarkets, Scientific Advisory Committee on Nutrition and Committee on Toxicity, Scottish Government, Seafish, Seafish, Seafish, Shepherd C.J., SOCA, STECF, STECF, Trussell Trust, Turner R.K., Turner R.K., UK Government, UK Government, UK Government, UK Government, UK Government, UK Government, UK Government, UK Government, Verner‐Jeffreys D.W., Warner K., World Commission on Environment and Development, World Health Organization   +85 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source