Results 11 to 20 of about 2,559,900 (249)
Establishing Confidence in Safety Assessment Evidence [PDF]
, 2012 With the increased complexity and higher safety commitment of modern safety–critical systems, safety assessment models of these systems are increasingly complicated and obscure.
Sun, Linling
core +6 more sources
Incremental Assurance Through Eliminative Argumentation [PDF]
, 2023 An assurance case for a critical system is valid for that system at a particular point in time, such as when the system is delivered to a certification authority for review.
Weinstock, Charles +3 more
core +1 more source
Frontiers in Pharmacology, 2022 Ethical and legal considerations have led to increased use of non-animal methods to evaluate the safety of chemicals for human use. We describe the development and qualification of a physiologically-based kinetics (PBK) model for the cosmetic UV filter ...
Abdulkarim Najjar +10 more
doaj +1 more source
An Assurance Framework for Independent Co-assurance of Safety and Security [PDF]
, 2018 Integrated safety and security assurance for complex systems is difficult for many technical and socio-technical reasons, such as mismatched processes, inadequate information, differing use of language and philosophies, etc.
Johnson, Nikita, Kelly, Tim
core +1 more source
Genes and Environment, 2022 Background Several rodent models with chemically induced colon cancer have been developed. Among these models, dextran sulfate sodium (DSS), a colitis inducer, combined with azoxymethane as a colon mutagenic carcinogen, is commonly used.
Atsushi Hakura +4 more
doaj +1 more source
Concepts of Safety Critical Systems Unification Approach & Security Assurance Process
, 2020 The security assurance of computer-based systems that rely on safety and security assurance, such as consistency, durability, efficiency and accessibility, require or need resources. This targets the System-of-Systems (SoS) problems with the exception of
Nabi, Faisal +5 more
core +1 more source
Airborne Separation Assurance Systems: towards a work programme to prove safety [PDF]
, 2004 With Full Delegation Airborne Separation Assurance System (ASAS), separation control would be delegated to the (properly equipped) aircraft, i.e. aircraft pilots are responsible for aircraft separation.
Peter Brooker, Brooker, Peter
core +1 more source
Constructing safety assurance cases for medical devices
, 2022 S.40-45This paper lays out a approach for safety assurance case argumentation. The approach links together in a principled manner a device's highest-level safety claims, operating environments and hazards; and its safety requirements, final ...
Ray, A., Cleaveland, R.
core +1 more source
Probative blindness and false assurance about safety [PDF]
, 2017 Safety activities may provide assurance of safety even where such assurance is unwarranted. This phenomenon – which we will call “probative blindness” – is evident both in hindsight analysis of accidents and in the daily practice of safety work.
Rae, Andrew John +5 more
core +1 more source
Life cycle assessment needs predictive spatial modelling for biodiversity and ecosystem services
Nature Communications, 2017 Life cycle assessments are used by corporations to determine the sustainability of raw source materials. Here, Chaplin-Krameret al. develop an improved life cycle assessment approach incorporating spatial variation in land-use change, and apply this ...
Rebecca Chaplin-Kramer +14 more
doaj +1 more source