Results 121 to 130 of about 866,873 (340)
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Securitas Mare - Crowd and Crisis Management [PDF]
TransNav, 2007 Shipping is by nature a genuinely international activity, with strict requirements for harmonized and equal training, regardless of where it is conducted. IMO?s model courses aims to give guidance in this respect. However, each signatory party to STCW-95
Christer Bergquist
doaj
MONALISA 2.0 and the sea traffic management - a concept creating the need for new maritime information standards and software solutions [PDF]
, 2015 Postprint (published ...
Castells Sanabra, Marcel·la +3 more
core
Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
The MarEng Project - a Tool for Enhancing Safety in Navigation and Maritime Transport [PDF]
TransNav, 2007 In the paper the MarEng project is presented as a tool for enhancing safety in navigation and maritime transport.
Barbara Katarzynska
doaj
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Regulation of the Turkish Straits: UNCLOS as an Alternative to the Treaty of Montreux and the 1994 Maritime Traffic Regulations for the Turkish Straits and Marmara Region [PDF]
, 1998 This Note discusses the need for a modern international legal regime that would address navigational and environmental safety in the Turkish Straits in a manner consistent with customary international law of the transit passage through the straits used ...
Pavlyuk, Serge V.
core +1 more source
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Reducing the impact of wave attack: dunes as natural buffers [PDF]
Coastal dune systems, with their self-regenerating capacity after storm erosion, represent natural defense zones against flooding of the hinterland. Condition: the total dune volume exceeds a certain minimum value related to the safety standard. As such,
Stroosnijder, L.
core +1 more source
Tracking Report 2009 Adidas Group, Vietnam 500084173H [PDF]
, 2009 This document is part of a digital collection provided by the Martin P. Catherwood Library, ILR School, Cornell University, pertaining to the effects of globalization on the workplace worldwide.
Fair Labor Association
core +2 more sources